| The influence of substance P on oviductal, duodenal and blood pressure in the anaesthetized domestic hen. | |
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MedLine Citation:
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PMID: 2476885 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In 13 anaesthetized hens in the peak phase of their first laying year the influence of intravenously injected substance P (SP), 1-10 micrograms/animal, on oviductal pressure, duodenal pressure, blood pressure and heart rate has been studied within 5 h of oviposition. The neuropeptide induced a significant pressure increase in the different segments of the oviduct (infundibulum, magnum, isthmus, uterus and vagina) as well as in the duodenum. Blood pressure revealed a distinct biphasic response: a short period of hypotension accompanied by a tachycardia and a more pronounced and sustained hypertension, inducing a subsequent bradycardia. The complexity of the observed effects demonstrates the overall impact of intravenously administered SP on the anaesthetized hen. |
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Authors:
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V De Saedeleer; E Wechsung; A Houvenaghel |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Veterinary research communications Volume: 13 ISSN: 0165-7380 ISO Abbreviation: Vet. Res. Commun. Publication Date: 1989 |
Date Detail:
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Created Date: 1989-10-25 Completed Date: 1989-10-25 Revised Date: 2003-11-14 |
Medline Journal Info:
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Nlm Unique ID: 8100520 Medline TA: Vet Res Commun Country: NETHERLANDS |
Other Details:
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Languages: eng Pagination: 183-91 Citation Subset: IM |
Affiliation:
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Laboratory of Veterinary Physiology, University of Antwerp, State University Centre, Belgium. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Analysis of Variance Anesthesia / veterinary Animals Blood Pressure / drug effects* Chickens / physiology* Dose-Response Relationship, Drug Duodenum / drug effects*, physiology Electrocardiography / veterinary Female Gastrointestinal Motility / drug effects Heart Rate / drug effects Oviducts / drug effects*, physiology Pressure Regression Analysis Substance P / pharmacology* |
| Chemical | |
Reg. No./Substance:
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33507-63-0/Substance P |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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