Document Detail

The influence of substance P on oviductal, duodenal and blood pressure in the anaesthetized domestic hen.
MedLine Citation:
PMID:  2476885     Owner:  NLM     Status:  MEDLINE    
In 13 anaesthetized hens in the peak phase of their first laying year the influence of intravenously injected substance P (SP), 1-10 micrograms/animal, on oviductal pressure, duodenal pressure, blood pressure and heart rate has been studied within 5 h of oviposition. The neuropeptide induced a significant pressure increase in the different segments of the oviduct (infundibulum, magnum, isthmus, uterus and vagina) as well as in the duodenum. Blood pressure revealed a distinct biphasic response: a short period of hypotension accompanied by a tachycardia and a more pronounced and sustained hypertension, inducing a subsequent bradycardia. The complexity of the observed effects demonstrates the overall impact of intravenously administered SP on the anaesthetized hen.
V De Saedeleer; E Wechsung; A Houvenaghel
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Veterinary research communications     Volume:  13     ISSN:  0165-7380     ISO Abbreviation:  Vet. Res. Commun.     Publication Date:  1989  
Date Detail:
Created Date:  1989-10-25     Completed Date:  1989-10-25     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  8100520     Medline TA:  Vet Res Commun     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  183-91     Citation Subset:  IM    
Laboratory of Veterinary Physiology, University of Antwerp, State University Centre, Belgium.
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MeSH Terms
Analysis of Variance
Anesthesia / veterinary
Blood Pressure / drug effects*
Chickens / physiology*
Dose-Response Relationship, Drug
Duodenum / drug effects*,  physiology
Electrocardiography / veterinary
Gastrointestinal Motility / drug effects
Heart Rate / drug effects
Oviducts / drug effects*,  physiology
Regression Analysis
Substance P / pharmacology*
Reg. No./Substance:
33507-63-0/Substance P

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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