Document Detail

The influence of spontaneous termination of atrial fibrillation on P wave-triggered signal-averaged electrocardiogram.
MedLine Citation:
PMID:  12559547     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Prolongation of total filtered P wave duration (Ad) and low root mean square voltages for the last 20 ms of the P wave (LP20) on a P wave-triggered signal-averaged electrocardiogram (PSAECG) are typically observed in paroxysmal atrial fibrillation (PAF) patients. A shortening of atrial refractoriness and intra-atrial conduction delay (atrial remodeling) have been shown to occur in response to PAF. We, therefore, investigated the effects of spontaneous termination of PAF on the parameters of PSAECG. METHODS: We measured the Ad, LP20 and left atrial (LA) diameter by ultrasonic echocardiography before, within 1 h after, and 3 and 12 months after PAF termination in patients with no structural heart disease (n=11). RESULTS: The PAF duration was 16+/-5 h. The Ads before, within 1 h after, and 3 and 12 months after PAF were 137+/-4, 148+/-4, 137+/-6, and 135+/-7 ms, respectively. The Ad within 1 h after PAF was significantly (P<0.01) longer than at the other three acquisition points. Although the LP20 within 1 h after PAF termination was not significantly different from the other three points, the change in LP20 (within 1 h after PAF-before PAF, -1.1+/-0.4 microV) in the long PAF duration group was significantly (P<0.05) greater than that of the short PAF duration group. LA diameter was unchanged at all points. CONCLUSION: These data suggest that PAF results in prolongation of Ad after termination of PAF.
Fumio Kurogouchi; Takeshi Tomita; Takeshi Hanaoka; Tatsuya Usui; Toyohisa Miyashita; Masakazu Aruga; Yuuichi Katagiri; Manabu Takei; Mafumi Owa; Kendo Kiyosawa
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  International journal of cardiology     Volume:  87     ISSN:  0167-5273     ISO Abbreviation:  Int. J. Cardiol.     Publication Date:  2003 Feb 
Date Detail:
Created Date:  2003-01-31     Completed Date:  2003-05-29     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8200291     Medline TA:  Int J Cardiol     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  253-8     Citation Subset:  IM    
Second Department of Internal Medicine, Shinshu University, School of Medicine, 3-1-1 Asahi, Matsumoto, 390-8621, Nagano-ken, Japan.
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MeSH Terms
Anti-Arrhythmia Agents / therapeutic use
Atrial Fibrillation / complications,  diagnosis*,  drug therapy
Body Surface Potential Mapping
Echocardiography / methods
Electrocardiography / methods*
Follow-Up Studies
Middle Aged
Prospective Studies
Sampling Studies
Sensitivity and Specificity
Signal Processing, Computer-Assisted*
Statistics, Nonparametric
Tachycardia, Paroxysmal / complications,  diagnosis,  drug therapy
Ventricular Remodeling / physiology*
Reg. No./Substance:
0/Anti-Arrhythmia Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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