Document Detail

The influence of smoking on endovascular abdominal aortic aneurysm repair.
MedLine Citation:
PMID:  22325665     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: The main purpose of this study was to evaluate the influence of smoking on perioperative outcomes of endovascular aneurysm repair (EVAR), aneurysm sac behavior, abdominal aortic aneurysm (AAA) neck growth after EVAR, and its effect on stent graft migration during follow-up.
METHODS: Baseline characteristics and follow-up data were collected prospectively by patient record forms. Follow-up visits were scheduled at 1, 3, 6, 12, 18, and 24 months, and annually thereafter and included a clinical examination and imaging studies. Patients were stratified in three groups according to their smoking status as nonsmokers, former smokers, and smokers.
RESULTS: This study analyzed the data for 4176 nonsmokers, 2406 former smokers, and 2056 smokers who were enrolled prospectively in the European Collaborators on Stent-Graft Techniques for Aortic Aneurysm Repair (EUROSTAR) database. Compared with nonsmokers, smokers required more percutaneous transluminal angioplasty and stent placements during EVAR (P < .001), and stent graft migration occurred more often (hazard ratio, 1.45; 95% confidence interval, 1.03-2.05; P = .033). Nonsmokers had more late type II endoleaks than former smokers and smokers (58.5%, 55.9%, and 35.5%, respectively; P < .001). Smoking had no effect on aneurysm sac behavior or AAA neck growth after EVAR.
CONCLUSIONS: Smokers need more percutaneous transluminal angioplasty procedures and stents during EVAR. They have fewer late type II endoleaks during follow-up; however, smokers should be closely monitored because they have an increased risk of stent graft migration.
Dave Koole; Frans L Moll; Jacob Buth; Roel Hobo; Herman Zandvoort; Gerard Pasterkamp; Joost A van Herwaarden;
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Publication Detail:
Type:  Journal Article     Date:  2012-02-09
Journal Detail:
Title:  Journal of vascular surgery     Volume:  55     ISSN:  1097-6809     ISO Abbreviation:  J. Vasc. Surg.     Publication Date:  2012 Jun 
Date Detail:
Created Date:  2012-05-21     Completed Date:  2012-07-18     Revised Date:  2012-10-03    
Medline Journal Info:
Nlm Unique ID:  8407742     Medline TA:  J Vasc Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1581-6     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 Society for Vascular Surgery. Published by Mosby, Inc. All rights reserved.
Department of Vascular Surgery, University Medical Center Utrecht, Utrecht, The Netherlands.
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MeSH Terms
Aged, 80 and over
Angioplasty, Balloon / adverse effects*,  instrumentation,  mortality
Aortic Aneurysm, Abdominal / mortality,  surgery*
Blood Vessel Prosthesis
Blood Vessel Prosthesis Implantation / adverse effects*,  instrumentation,  mortality
Chi-Square Distribution
Endoleak / etiology*,  mortality
Foreign-Body Migration / etiology*,  mortality
Kaplan-Meier Estimate
Middle Aged
Multivariate Analysis
Proportional Hazards Models
Prospective Studies
Prosthesis Design
Risk Assessment
Risk Factors
Smoking / adverse effects*,  prevention & control
Smoking Cessation
Time Factors
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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