| The influence of saliva on the dissolution of calcium fluoride after application of different fluoride gels in vitro. | |
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MedLine Citation:
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PMID: 20806102 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To determine the formation and dissolution of calcium fluoride on the enamel surface after application of two fluoride gel-saliva mixtures. METHOD AND MATERIALS: From each of 80 bovine incisors, two enamel specimens were prepared and subjected to two different treatment procedures. In group 1, 80 specimens were treated with a mixture of an amine fluoride gel (1.25% F-; pH 5.2; 5 minutes) and human saliva. In group 2, 80 enamel blocks were subjected to a mixture of sodium fluoride gel (1.25% F; pH 5.5; 5 minutes) and human saliva. Subsequent to fluoride treatment, 40 specimens from each group were stored in human saliva and sterile water, respectively. Ten specimens were removed after each of 1 hour, 24 hours, 2 days, and 5 days and analyzed according to potassium hydroxide-soluble fluoride. RESULTS: Application of amine fluoride gel resulted in a higher amount of potassium hydroxide-soluble fluoride than did sodium fluoride gel 1 hour after application. Saliva exerted an inhibitory effect according to the dissolution rate of calcium fluoride. However, after 5 days, more than 90% of the precipitated calcium fluoride was dissolved in the amine fluoride group, and almost all potassium hydroxide-soluble fluoride was lost in the sodium fluoride group. Calcium fluoride apparently dissolves rapidly, even at almost neutral pH. CONCLUSION: Considering the limitations of an in vitro study, it is concluded that highly concentrated fluoride gels should be applied at an adequate frequency to reestablish a calcium fluoride-like layer. |
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Authors:
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Elmar Hellwig; Olga Polydorou; Adrian Lussi; Andrej M Kielbassa; Markus J Altenburger |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Quintessence international (Berlin, Germany : 1985) Volume: 41 ISSN: 1936-7163 ISO Abbreviation: Quintessence Int Publication Date: 2010 Oct |
Date Detail:
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Created Date: 2010-08-31 Completed Date: 2010-12-23 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0342677 Medline TA: Quintessence Int Country: Germany |
Other Details:
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Languages: eng Pagination: 773-7 Citation Subset: D |
Affiliation:
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Department of Operative Dentistry and Periodontology, University Clinic of Dentistry, Albert-Ludwigs-University Freiburg, Freiburg, Germany. Elmar.Hellwig@uniklinik-freiburg.de |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Calcium Fluoride / pharmacokinetics* Cariostatic Agents / administration & dosage*, analysis Cattle Chemical Precipitation Dental Enamel / drug effects, metabolism* Diamines / administration & dosage Fluorides / administration & dosage*, analysis Gels Humans Hydrogen-Ion Concentration Hydroxides / chemistry Potassium Compounds / chemistry Saliva / metabolism* Sodium Fluoride / administration & dosage Solubility Time Factors Water / chemistry |
| Chemical | |
Reg. No./Substance:
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0/Cariostatic Agents; 0/Diamines; 0/Fluorides; 0/Gels; 0/Hydroxides; 0/Olaflur; 0/Potassium Compounds; 1310-58-3/potassium hydroxide; 7681-49-4/Sodium Fluoride; 7732-18-5/Water; 7789-75-5/Calcium Fluoride |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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