| The influence of right heart catheterisation on pulmonary arterial pressure in chronic heart failure: relationship to neuroendocrinal changes. | |
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MedLine Citation:
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PMID: 1837009 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Continuous ambulatory measurement of pulmonary arterial pressure was used to investigate changes following right heart catheterisation in patients with chronic heart failure. Ten males, mean age 56 years, with chronic heart failure, underwent 24 hour pressure recording using a micromanometer tipped catheter with in vivo calibration and frequency modulated recording. Eight patients were taking diuretics and 3 vasodilators. Blood was drawn for catecholamines, plasma renin activity and atrial natriuretic peptide 1 hour before catheterisation (-1 h), at the time of catheterisation (0 h) and 1, 2, 3, 4 and 6 hours later and aldosterone, cortisol and growth hormone at -1, 0 and 6 hours. Analysis of variance was used to determine changes in pulmonary arterial pressure, heart rate and hormones from the time of catheterisation in lying, sitting and standing postures. There was no significant change in pulmonary arterial pressure or heart rate over the 12 hours following or 24 hours after catheterisation in any posture. In the majority of patients plasma noradrenaline, plasma renin activity, atrial natriuretic peptide, aldosterone and cortisol were elevated. There was no significant change in hormone levels during the 6 hours following catheterisation. These findings suggest that the effect of invasive haemodynamic monitoring and chronic medical therapy on central haemodynamics is minor, and that a delay between insertion of catheters and measurement of pressure is unnecessary. |
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Authors:
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J S Gibbs; R Ferrari; J Keegan; C Ceconi; C Wright; K M Fox; P A Poole-Wilson |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: International journal of cardiology Volume: 33 ISSN: 0167-5273 ISO Abbreviation: Int. J. Cardiol. Publication Date: 1991 Dec |
Date Detail:
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Created Date: 1992-02-13 Completed Date: 1992-02-13 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8200291 Medline TA: Int J Cardiol Country: NETHERLANDS |
Other Details:
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Languages: eng Pagination: 365-76 Citation Subset: IM |
Affiliation:
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National Heart Hospital, London, U.K. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aldosterone / blood Atrial Natriuretic Factor / blood Chronic Disease Electrocardiography, Ambulatory Evaluation Studies as Topic Heart Catheterization / standards* Heart Failure / blood, diagnosis, physiopathology* Heart Rate Hormones / blood* Humans Hydrocortisone / blood Male Middle Aged Norepinephrine / blood Pulmonary Wedge Pressure* Renin / blood |
| Chemical | |
Reg. No./Substance:
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0/Hormones; 50-23-7/Hydrocortisone; 51-41-2/Norepinephrine; 52-39-1/Aldosterone; 85637-73-6/Atrial Natriuretic Factor; EC 3.4.23.15/Renin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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