Document Detail

The influence of pregnancy on relapses in multiple sclerosis: a cohort study.
MedLine Citation:
PMID:  1776387     Owner:  NLM     Status:  MEDLINE    
The influence of pregnancy on the relapse rate (number of relapses per person per year) in MS was analysed for 52 women who had a pregnancy during the disease. The relapse rate was lower during the pregnancy-year (9 months of pregnancy and 6 months immediately post partum) than the non-pregnancy time. There was a heterogeneous pattern during the pregnancy-year with a sharp decrease in the relapse rate observed during pregnancy and a slight non-significant increase in the puerperium: both these relapse rates were compared with figures observed in the same group of women during the non-pregnancy time. Pregnancy does not appear to be a period at greater risk for exacerbations but, on the contrary it seems to act, on the whole, as a protective event. These data allow physicians to provide reassuring counselling to women.
S Bernardi; M G Grasso; R Bertollini; F Orzi; C Fieschi
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta neurologica Scandinavica     Volume:  84     ISSN:  0001-6314     ISO Abbreviation:  Acta Neurol. Scand.     Publication Date:  1991 Nov 
Date Detail:
Created Date:  1992-02-28     Completed Date:  1992-02-28     Revised Date:  2006-08-16    
Medline Journal Info:
Nlm Unique ID:  0370336     Medline TA:  Acta Neurol Scand     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  403-6     Citation Subset:  IM    
Department of Neurological Sciences, University of Rome, Italy.
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MeSH Terms
Cohort Studies
Gestational Age
Infant, Newborn
Middle Aged
Multiple Sclerosis / diagnosis*
Neurologic Examination*
Pregnancy Complications / diagnosis*
Puerperal Disorders / diagnosis
Comment In:
Acta Neurol Scand. 1992 Aug;86(2):222-3   [PMID:  1414236 ]

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