| The influence of normobaric hyperoxia on hydroxyproline content and collagenase and elastase activities in rat lung. | |
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MedLine Citation:
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PMID: 8055048 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The influence of 12, 24 and 48 hrs of normobaric hyperoxia on hydroxyproline content and both collagenase and elastase activities in rat lung was investigated. The rise in hydroxyproline level in lung after only 24 hrs of hyperoxia was observed. In bronchoalveolar lavage, however, the level of this amino acid remains unchanged during the whole time of the experiment. Collagenase activity decreased significantly after 12 hrs of hyperoxia, and then decreased gradually. Elastase activity was diminished after 48 hrs of hyperoxia. It is suggested that breathing with pure oxygen induce changes in collagenase activity long before the changes in elastase activity or hydroxyproline content. |
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Authors:
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A Ledwozyw; B Borowicz |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Archivum veterinarium Polonicum / Polish Academy of Sciences, Committee of Veterinary Sciences Volume: 33 ISSN: 1230-5359 ISO Abbreviation: Arch Vet Pol Publication Date: 1993 |
Date Detail:
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Created Date: 1994-09-12 Completed Date: 1994-09-12 Revised Date: 2003-11-14 |
Medline Journal Info:
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Nlm Unique ID: 9313674 Medline TA: Arch Vet Pol Country: POLAND |
Other Details:
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Languages: eng Pagination: 117-22 Citation Subset: IM |
Affiliation:
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Department of Pathophysiology, Agricultural University, Lublin, Poland. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Bronchoalveolar Lavage Fluid Collagenases / metabolism* Hydroxyproline / metabolism* Lung / enzymology* Male Oxygen / pharmacology* Pancreatic Elastase / metabolism* Rats Rats, Wistar |
| Chemical | |
Reg. No./Substance:
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51-35-4/Hydroxyproline; 7782-44-7/Oxygen; EC 3.4.21.36/Pancreatic Elastase; EC 3.4.24.-/Collagenases |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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