Document Detail

The influence of moderate-intensity noise on the click-evoked compound action potential of the guinea pig, Cavia porcellus.
MedLine Citation:
PMID:  4074186     Owner:  NLM     Status:  MEDLINE    
Noise-induced alterations of the click-evoked compound potential (CAP) were studied by means of electrodes chronically implanted near the round window in 15 pigmented guinea pigs aged 3-6 months. The potentials were recorded before, during and after exposure to continuous pink noise maintained at an intensity of 80, 90 or 100 dB SPL for 120 h. During the exposure phase the CAP thresholds of all the animals tested increased exponentially, nearly leveling out by approximately 48 h to form an asymptotic threshold shift. Recovery after the end of exposure also occurred exponentially, with a return to the original threshold for neural excitation after at most 72 h. There was no detectable change in amplitude, latency or inter-peak interval of the CAP when correlated with the change in threshold.
M Walger; U Schmidt; H von Wedel
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Archives of oto-rhino-laryngology     Volume:  242     ISSN:  0302-9530     ISO Abbreviation:  Arch Otorhinolaryngol     Publication Date:  1985  
Date Detail:
Created Date:  1986-01-21     Completed Date:  1986-01-21     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0414105     Medline TA:  Arch Otorhinolaryngol     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  279-85     Citation Subset:  IM    
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MeSH Terms
Acoustic Stimulation / methods
Differential Threshold
Electrodes, Implanted
Evoked Potentials, Auditory*
Guinea Pigs

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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