Document Detail


The influence of modeling separate neuromuscular compartments on the force and moment generating capacities of muscles of the feline hindlimb.
MedLine Citation:
PMID:  20670052     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Functional electrical stimulation (FES) has the capacity to regenerate motion for individuals with spinal cord injuries. However, it is not straightforward to determine the stimulation parameters to generate a coordinated movement. Musculoskeletal models can provide a noninvasive simulation environment to estimate muscle force and activation timing sequences for a variety of tasks. Therefore, the purpose of this study was to develop a musculoskeletal model of the feline hindlimb for simulations to determine stimulation parameters for intrafascicular multielectrode stimulation (a method of FES). Additionally, we aimed to explore the differences in modeling neuromuscular compartments compared with representing these muscles as a single line of action. When comparing the modeled neuromuscular compartments of biceps femoris, sartorius, and semimembranosus to representations of these muscles as a single line of action, we observed that modeling the neuromuscular compartments of these three muscles generated different force and moment generating capacities when compared with single muscle representations. Differences as large as 4 N m (approximately 400% in biceps femoris) were computed between the summed moments of the neuromuscular compartments and the single muscle representations. Therefore, modeling neuromuscular compartments may be necessary to represent physiologically reasonable force and moment generating capacities of the feline hindlimb.
Authors:
Lisa N MacFadden; Nicholas A T Brown
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural    
Journal Detail:
Title:  Journal of biomechanical engineering     Volume:  132     ISSN:  1528-8951     ISO Abbreviation:  J Biomech Eng     Publication Date:  2010 Aug 
Date Detail:
Created Date:  2010-07-30     Completed Date:  2010-12-27     Revised Date:  2010-12-28    
Medline Journal Info:
Nlm Unique ID:  7909584     Medline TA:  J Biomech Eng     Country:  United States    
Other Details:
Languages:  eng     Pagination:  081003     Citation Subset:  IM    
Affiliation:
Department of Bioengineering, University of Utah, Salt Lake City, UT 84112, USA. lisa.macfadden@utah.edu
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MeSH Terms
Descriptor/Qualifier:
Animals
Cats
Computer Simulation
Hindlimb / physiology*
Joints / physiology*
Models, Biological*
Muscle Contraction / physiology*
Stress, Mechanical
Torque
Grant Support
ID/Acronym/Agency:
2R01-NS039677-05A1/NS/NINDS NIH HHS
Comments/Corrections
Erratum In:
J Biomech Eng. 2010 Dec; 132(12):127001

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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