Document Detail

The influence of material property and morphological parameters on specimen-specific finite element models of porcine vertebral bodies.
MedLine Citation:
PMID:  16584740     Owner:  NLM     Status:  MEDLINE    
The use of finite element (FE) methods in spinal research is increasing, but there is only limited information available on the influence of different input parameters on the model predictions. The aim of this study was to investigate the role of these parameters in FE models of the vertebral body. Experimental tests were undertaken on porcine lumbar vertebral bodies and scans of the specimens were used to create specimen-specific FE models. Three models were created for each specimen with combinations of generic and specimen-specific parameters. Stiffness and strength predictions were also made directly from the specimen trabecular bone volume fraction (BVF) and cross-sectional area (CSA). The agreement between the experimental results and the FE models with generic morphology was poorer (concordance coefficients = 0.058, 0.125 for stiffness, strength) than those made from the BVF and CSA (concordance coefficients = 0.638, 0.609). The greatest levels of agreement were found with the morphologically specific models including element-specific material properties (concordance coefficients = 0.881, 0.752). This indicates that highly specific models, both in terms of morphology and bone quality, are necessary if the FE tool is to be used effectively for spinal research and clinical practice.
Ruth K Wilcox
Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't     Date:  2006-04-11
Journal Detail:
Title:  Journal of biomechanics     Volume:  40     ISSN:  0021-9290     ISO Abbreviation:  J Biomech     Publication Date:  2007  
Date Detail:
Created Date:  2007-01-22     Completed Date:  2007-03-20     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0157375     Medline TA:  J Biomech     Country:  United States    
Other Details:
Languages:  eng     Pagination:  669-73     Citation Subset:  IM    
School of Mechanical Engineering, University of Leeds, Leeds, LS2 9JT, UK.
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MeSH Terms
Compressive Strength
Finite Element Analysis*
Models, Biological*
Spine / anatomy & histology*,  physiology*
Swine / anatomy & histology,  physiology

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