| The influence of late pregnancy and lactation on bone metabolism in mares. | |
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MedLine Citation:
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PMID: 20022348 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Pregnancy and lactation are periods of significant influence on bone metabolism that has not been investigated in equines. To examine the influence of late pregnancy and lactation on bone metabolism in mares, the changes in the blood serum/plasma total calcium (Ca), inorganic phosphates (Pi), pyridinoline (Pyd) and 17beta-estradiol (E2) concentration and the bone alkaline phosphatase (BAP) activity were investigated. The samples were taken from 11 mares on 60+/-10 and 20+/-10 days before foaling, and 20+/-10 and 60+/-10 days after foaling. The concentration/activity of Ca, Pi, Pyd and BAP increased significantly in early lactation, but the Pyd than decreased in the 4th period. A significant correlation was observed between the E2 and bone metabolism parameters. The results indicate low maintenance of normocalcaemia with reduced bone synthesis in late pregnancy and prove the role of estradiol in bone metabolism in mares during pregnancy and lactation. |
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Authors:
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Natalija Filipović; Zvonko Stojević; Nikica Prvanović; Zvonimir Tucek |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2009-12-21 |
Journal Detail:
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Title: Research in veterinary science Volume: 88 ISSN: 1532-2661 ISO Abbreviation: Res. Vet. Sci. Publication Date: 2010 Jun |
Date Detail:
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Created Date: 2010-04-29 Completed Date: 2010-08-19 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0401300 Medline TA: Res Vet Sci Country: England |
Other Details:
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Languages: eng Pagination: 405-10 Citation Subset: IM |
Copyright Information:
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Copyright 2009 Elsevier Ltd. All rights reserved. |
Affiliation:
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Department of Physiology and Radiobiology, Faculty of Veterinary Medicine, University of Zagreb, Heinzelova 55, 10000 Zagreb, Croatia. nfilipovic@vef.hr |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aging
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physiology* Alkaline Phosphatase / blood Animals Bone and Bones / enzymology, metabolism* Calcium / blood Estradiol / blood Female Horses Lactation / physiology* Phosphates / blood Pregnancy Pregnancy, Animal* / physiology |
| Chemical | |
Reg. No./Substance:
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0/Phosphates; 50-28-2/Estradiol; 7440-70-2/Calcium; EC 3.1.3.1/Alkaline Phosphatase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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