Document Detail


The influence of inflammation of the human male genital tract on secretion of the seminal markers alpha-glucosidase, glycerophosphocholine, carnitine, fructose and citric acid.
MedLine Citation:
PMID:  2283178     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Biochemical analysis was made of specific accessory gland products in the ejaculates of 362 men suffering from various acute inflammatory diseases of the reproductive tract and 33 normozoospermic patients acting as controls. The ejaculate content of the epididymal markers alpha-glucosidase and L-carnitine, but not glycerophosphocholine, was significantly reduced in ejaculates from men with epididymitis; citric acid was reduced in men suffering from prostatitis; both citric acid and alpha-glucosidase were reduced in men suffering from adnexitis. The ejaculate content of epididymal and prostatic markers in prostato-urethritis (adnexitis), where the exact localization of the inflammation was unclear, was not as low as in epididymitis or prostatitis. Seminal vesicle function, as judged from semen volumes and seminal fructose, was not different in these groups of patients. The results, although strongly related to the clinical diagnosis, were unrelated to the microbiological flora of the semen and indicate that both the epididymis and the prostate glands are involved in some forms of adnexitis.
Authors:
T G Cooper; W Weidner; E Nieschlag
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  International journal of andrology     Volume:  13     ISSN:  0105-6263     ISO Abbreviation:  Int. J. Androl.     Publication Date:  1990 Oct 
Date Detail:
Created Date:  1991-03-15     Completed Date:  1991-03-15     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8000141     Medline TA:  Int J Androl     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  329-36     Citation Subset:  IM    
Affiliation:
Max Planck Clinical Research Unit for Reproductive Medicine, Münster, FRG.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Analysis of Variance
Carnitine / secretion
Citrates / metabolism
Citric Acid
Epididymis / secretion
Fructose / secretion
Genital Diseases, Male / metabolism*,  microbiology
Glycerylphosphorylcholine / secretion
Humans
Inflammation / metabolism
Male
Middle Aged
Prostate / secretion
Semen / metabolism*,  microbiology
Seminal Vesicles / secretion
alpha-Glucosidases / secretion
Chemical
Reg. No./Substance:
0/Citrates; 30237-26-4/Fructose; 541-15-1/Carnitine; 563-24-6/Glycerylphosphorylcholine; 77-92-9/Citric Acid; EC 3.2.1.20/alpha-Glucosidases

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