Document Detail

The influence of increased dietary linoleate on essential hypertension in man.
MedLine Citation:
PMID:  742306     Owner:  NLM     Status:  MEDLINE    
A pilot study testing the hypothesis of a blood pressure lowering effect of polyunsaturated fatty acids was conducted in Evans County, Georgia. A moderate increase of dietary linoleic acid significantly decreased diastolic blood pressure in eight borderline hypertensives who were otherwise healthy, within four weeks. The change was not due to a reduced sodium content of the diet. A significant increase in creatinine excretion and clearance was noted, indicating an improvement in kidney function which might explain the blood pressure lowering effect of the fat-modified diet.
A J Vergroesen; A I Fleischman; H U Comberg; S Heyden; C G Hames
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Acta biologica et medica Germanica     Volume:  37     ISSN:  0001-5318     ISO Abbreviation:  Acta Biol. Med. Ger.     Publication Date:  1978  
Date Detail:
Created Date:  1979-04-25     Completed Date:  1979-04-25     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370276     Medline TA:  Acta Biol Med Ger     Country:  GERMANY, EAST    
Other Details:
Languages:  eng     Pagination:  879-83     Citation Subset:  IM    
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MeSH Terms
Blood Pressure / drug effects
Dietary Fats*
Hypertension / blood,  physiopathology*,  urine
Linoleic Acids / diagnostic use*
Reg. No./Substance:
0/Dietary Fats; 0/Linoleic Acids

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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