Document Detail

The influence of hyperventilation on the measurement of stroke volume using a CO2 rebreathing method.
MedLine Citation:
PMID:  3084237     Owner:  NLM     Status:  MEDLINE    
The influence of different degrees of hyperventilation on stroke volume measured with a CO2 rebreathing method was studied in seven normal subjects and seven patients with aortic regurgitation. Hyperventilation was initially performed with a rebreathing rate of 30 min-1 and a tidal volume corresponding to 60% of the subject's vital capacity. The tidal volume was then randomly decreased or increased by 0.5 and 1.01 and the procedure was repeated with rebreathing rates of 25 and 35 min-1. The possible influence of habituation to repeated measurements was tested in seven of the subjects. No significant differences in response to hyperventilation of stroke volume, cardiac output or heart rate were found between normal subjects and patients. When the tidal volume was increased, there was a significant increase in heart rate and also an increase in cardiac output, which was significant when comparing measurements performed with the lowest and highest tidal volumes. When comparing initial and final measurements, there was a significant decrease in heart rate and a tendency to decrease in cardiac output. Stroke volume was not affected by variations in rebreathing rate from 25 to 35 min-1 or tidal volume changes of +/- 0.51 and was also unaffected by repeated measurements.
J Ohlsson; B Wranne
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  European journal of applied physiology and occupational physiology     Volume:  55     ISSN:  0301-5548     ISO Abbreviation:  Eur J Appl Physiol Occup Physiol     Publication Date:  1986  
Date Detail:
Created Date:  1986-06-06     Completed Date:  1986-06-06     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0410266     Medline TA:  Eur J Appl Physiol Occup Physiol     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  19-23     Citation Subset:  IM    
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MeSH Terms
Carbon Dioxide / diagnostic use
Cardiac Output
Heart Rate
Hyperventilation / physiopathology*
Partial Pressure
Physiology / methods
Stroke Volume*
Tidal Volume
Reg. No./Substance:
124-38-9/Carbon Dioxide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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