| The influence of high temperature on human cells in culture, their sensitivity to viruses and their interferon-producing capacity. | |
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MedLine Citation:
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PMID: 2437783 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The influence of extremely high temperatures on the course of virus infection in vitro was studied. It has been shown that exposure of human cells (continuous cell line of embryonal skin-muscle tissue, donor blood leukocytes) to 43 degrees C leads to a significant increase in their sensitivity to cytopathic action of the viruses tested. Noteworthy, the reproduction of these viruses under tested conditions did not differ from their reproduction in control cells. A dramatic inhibitory effect of high temperatures on the interferon-producing capacity of cells was observed. |
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Authors:
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A I Kognovitskaya; A I Bokhonko; T V Mamontova; T G Orlova |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Acta virologica Volume: 31 ISSN: 0001-723X ISO Abbreviation: Acta Virol. Publication Date: 1987 Jan |
Date Detail:
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Created Date: 1987-06-08 Completed Date: 1987-06-08 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 0370401 Medline TA: Acta Virol Country: CZECHOSLOVAKIA |
Other Details:
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Languages: eng Pagination: 7-12 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Cell Line Cytopathogenic Effect, Viral Encephalomyocarditis virus / growth & development* Hot Temperature Humans Influenza A virus / growth & development* Interferons / biosynthesis* Newcastle disease virus / immunology* Vesicular stomatitis Indiana virus / growth & development* |
| Chemical | |
Reg. No./Substance:
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9008-11-1/Interferons |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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