| The influence of glycerol on the Ca flux in the isolated perfused rat heart. | |
| | |
MedLine Citation:
|
PMID: 938437 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Perfusion of the isolated rat heart with a fluid containing 800mM glycerol in addition to its normal constituents causes a contraction height decrease of about 50%. A change to normal perfusion fluid causes a period of contracture to occur. After this period the heart is perfectly viable. Mechanical and osmotic effects could be ruled out as possible causes. No gross disturbances were seen in the electron micrographs. An effect on intermediary metabolism is equally unlikely. Presumably, we must seek the explanation in a direct effect of the glycerol on the Ca++ fluxes across the cellular and intracellular membranes. |
| | |
Authors:
|
H L Frank; H C Hemker |
Related Documents
:
|
1523217 - Cardiovascular effects of acetaldehyde in pithed rats. 870147 - Phosphatidic acid synthesis in the heart. 1. effect of age and species difference in th... 9718077 - Melatonin, a pineal hormone with antioxidant property, protects against adriamycin card... 12074987 - Cardioprotective abilities of white wine. 2333147 - Long-term chemical sympathectomy leads to an increase of neuropeptide y immunoreactivit... 6690477 - Selective vulnerability of the medullary thick ascending limb to anoxia in the isolated... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Basic research in cardiology Volume: 71 ISSN: 0300-8428 ISO Abbreviation: Basic Res. Cardiol. Publication Date: 1976 May-Jun |
Date Detail:
|
Created Date: 1976-08-23 Completed Date: 1976-08-23 Revised Date: 2003-11-14 |
Medline Journal Info:
|
Nlm Unique ID: 0360342 Medline TA: Basic Res Cardiol Country: GERMANY, WEST |
Other Details:
|
Languages: eng Pagination: 252-62 Citation Subset: IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Calcium / metabolism* Cell Membrane Electrocardiography Female Glycerol / pharmacology* Heart / drug effects* Myocardial Contraction Myocardium / metabolism Perfusion Rats |
| Chemical | |
Reg. No./Substance:
|
56-81-5/Glycerol; 7440-70-2/Calcium |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Influence of tachycardia on regional myocardial flow in chronic experimental coronary occlusion.
Next Document: The role of myocardial edema in the left ventricular diastolic stiffness.