| The influence of glucose-insulin-kalium mixture (GIK) on the selected parameters of acid-base balance in acute myocardial infarction. | |
MedLine Citation:
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PMID: 11977294 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The aim of the paper was assessing the influence of polarizing GIK mixture on the selected indicators of acid-base equilibrium in patients with acute myocardial infarction treated fibrinolytically. The patients had arterial blood taken in order to check pH, partial pressure of oxygen and carbon dioxide, and the content of bicarbonates. Changes in the examined parameters in the group obtaining GIK and in the one obtaining placebo were subject to critical analysis. Changes in gasometric parameters taking place under the influence of GIK administered to patients were also analysed according to the site of infarction. It was observed that after 24 hours from the beginning of infusion pH increased and pCO2 decreased in comparison to the initial examination. These changes did not depend on the kind of applied infusion (GIK or physiological saline infusion), no significant changes in bicarbonates being observed. However, after applying GIK infusion, an increase in oxygen pressure in comparison with the control group was observed, and differences between the groups were within the boundaries of significance. Neither was there observed any influence of infarction site on changes in the assessed parameters of acid-base equilibrium in the group treated with GIK nor in the one receiving placebo. |
Authors:
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E Rymarz; J Mosiewicz; J Hanzlik |
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Publication Detail:
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Type: Clinical Trial; Journal Article; Randomized Controlled Trial |
Journal Detail:
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Title: Annales Universitatis Mariae Curie-Skłodowska. Sectio D: Medicina Volume: 56 ISSN: 0066-2240 ISO Abbreviation: Ann Univ Mariae Curie Sklodowska Med Publication Date: 2001 |
Date Detail:
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Created Date: 2002-04-29 Completed Date: 2002-06-19 Revised Date: 2009-06-05 |
Medline Journal Info:
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Nlm Unique ID: 0414101 Medline TA: Ann Univ Mariae Curie Sklodowska Med Country: Poland |
Other Details:
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Languages: eng Pagination: 1-6 Citation Subset: IM |
Affiliation:
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1st Department of Internal Medicine, Medical University of Lublin. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Acid-Base Equilibrium
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drug effects Aged Cardioplegic Solutions / administration & dosage* Drug Administration Schedule Female Glucose / administration & dosage* Humans Insulin / administration & dosage* Male Middle Aged Myocardial Infarction / drug therapy*, metabolism* Potassium / administration & dosage* |
| Chemical | |
Reg. No./Substance:
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0/Cardioplegic Solutions; 0/glucose-insulin-potassium cardioplegic solution; 11061-68-0/Insulin; 50-99-7/Glucose; 7440-09-7/Potassium |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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