Document Detail

The influence of flunitrazepam on the blood gases during subarachnoid block in geriatric patients (author's transl)
MedLine Citation:
PMID:  6110385     Owner:  NLM     Status:  MEDLINE    
Fifty-three geriatric patients under subarachnoid block for orthopaedic surgery received flunitrazepam 0.3-0.4 mg intravenously. Blood gases were checked while breathing room air. This dose caused a significant but small respiratory depression (p less than 0.05). These results confirm other reports on flunitrazepam, but used without spinal anaesthesia. There was no case, however, who needed ventilatory support. Top up doses up to a total of 1 mg caused no further significant changes. We feel that Flunitrazepam is a useful drug for sedation during regional block including poor risk patients.
L Tonczar
Publication Detail:
Type:  English Abstract; Journal Article    
Journal Detail:
Title:  Der Anaesthesist     Volume:  29     ISSN:  0003-2417     ISO Abbreviation:  Anaesthesist     Publication Date:  1980 Sep 
Date Detail:
Created Date:  1981-04-24     Completed Date:  1981-04-24     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370525     Medline TA:  Anaesthesist     Country:  GERMANY, WEST    
Other Details:
Languages:  ger     Pagination:  487-9     Citation Subset:  IM    
Vernacular Title:
Beeinflussung der Blutgaswerte geriatrischer Patienten durch Flunitrazepam während subarachnoidaler Blockade.
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MeSH Terms
Anti-Anxiety Agents / pharmacology*
Carbon Dioxide / blood*
Flunitrazepam / pharmacology*
Nerve Block*
Oxygen / blood*
Preanesthetic Medication*
Subarachnoid Space
Reg. No./Substance:
0/Anti-Anxiety Agents; 124-38-9/Carbon Dioxide; 1622-62-4/Flunitrazepam; 7782-44-7/Oxygen

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