Document Detail

The influence of exercise and diet on myoglobin and metmyoglobin reductase in the rat.
MedLine Citation:
PMID:  7354234     Owner:  NLM     Status:  MEDLINE    
This study was designed to evaluate the influence of exercise and diet on selected aspects of heme protein metabolism in the rat. Two levels of treadmill exercise and three levels of dietary restriction were imposed on growing male rats over a 12-week experimental period. Neither training nor diet had any effect on erythrocyte NADH-MetHB reductase. The group undergoing the highest level of treadmill exercise had a significantly lower HB concentration. The activity of NADH-MetMB reductase was increased in the group undergoing the highest level of training and decreased in the groups whose diet was restricted by 25% and 35%. These changes were seen only in the soleus muscle. Other muscles, including the heart, psoas, and quadriceps were unaffected by either exercise of diet. Both levels of exercise were effective in increasing muscle MB concentration, but only in the quadriceps and soleus muscles. These data illustrate the adaptive nature of muscle MB and NADH-MetMB reductase. They also illustrate the different adaptive patterns of these two components of muscle.
L Hagler; R I Coppes; E W Askew; A L Hecker; R H Herman
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of laboratory and clinical medicine     Volume:  95     ISSN:  0022-2143     ISO Abbreviation:  J. Lab. Clin. Med.     Publication Date:  1980 Feb 
Date Detail:
Created Date:  1980-04-17     Completed Date:  1980-04-17     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0375375     Medline TA:  J Lab Clin Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  222-30     Citation Subset:  AIM; IM    
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MeSH Terms
Hemeproteins / metabolism
Metmyoglobin / metabolism
Myoglobin / metabolism*
Oxidoreductases / metabolism
Physical Exertion*
Reg. No./Substance:
0/Hemeproteins; 0/Myoglobin; 12772-23-5/Metmyoglobin; EC 1.-/Oxidoreductases

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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