| The influence of endometriosis on the success of gamete intrafallopian transfer (GIFT). | |
| | |
MedLine Citation:
|
PMID: 9048236 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
PURPOSE: Our purpose was to evaluate the outcomes of gamete intrafallopian transfer (GIFT) therapy in patients with endometriosis. METHODS: One hundred eight GIFT cycles performed under the indication of endometriosis were compared to 156 GIFT cycles with indications of other disease entities. A maximum of seven oocytes was transferred into one or both fimbriate ends with prepared spermatozoa. Clinical pregnancy rates and outcomes were evaluated according to Mantel-Haenszel's chi-square test. Multiple logistic regression analysis was performed to determine factors influencing the success on pregnancy in the total treatment cycles. RESULTS: The anthropological variables, such as age of patients, duration of infertility, and semen grading, were comparable in both groups. The responses to controlled ovarian hyperstimulation (COH) were progressively decreased while increasing the severity of endometriosis conditions such as nonendometriosis, mild-form endometriosis, and advanced-form endometriosis patients. However, there were no significant differences in the clinical pregnancy rates (40.4, 36.7, and 41.7%, respectively), multiple pregnancy rates (34.9, 27.3, and 45.0%, respectively), and early pregnancy loss rates (27.0, 18.2, and 30.0%, respectively). Multivariate statistics of pregnancy rates that adjusted the effects of patients' age, tubal health, presence of active endometriosis and/or endometriomas, number of oocytes transferred, and quality of sperm exhibited no statistical significance between endometriosis and nonendometriosis groups. CONCLUSIONS: Our data show that patients with records of endometriosis have both a decreased ovarian response to gonadotropin stimulation and a decreased number of retrieved oocytes. Since the number of oocytes needed for the GIFT procedure is limited, pregnancy results for patients in the study group were comparable with those for patients in the control group. |
| | |
Authors:
|
M Y Chang; C H Chiang; T T Hsieh; Y K Soong; K H Hsu |
Related Documents
:
|
1534486 - Recent advances in female infertility care. 3949036 - Preliminary experiences with gamete intrafallopian transfer (gift). 10050656 - Cag repeat length in the androgen receptor gene of infertile japanese males with oligoz... 9207576 - Randomized controlled trial of superovulation and insemination for infertility associat... 3640186 - Maternal-fetal attachment in relation to self-concept and anxiety. 2081806 - Comparison of concurrent pregnancy rates for in-vitro fertilization--embryo transfer, p... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Journal of assisted reproduction and genetics Volume: 14 ISSN: 1058-0468 ISO Abbreviation: J. Assist. Reprod. Genet. Publication Date: 1997 Feb |
Date Detail:
|
Created Date: 1997-05-08 Completed Date: 1997-05-08 Revised Date: 2013-02-19 |
Medline Journal Info:
|
Nlm Unique ID: 9206495 Medline TA: J Assist Reprod Genet Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 76-82 Citation Subset: IM |
Affiliation:
|
Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital, Taipei, Taiwan, ROC. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Analysis of Variance Anthropometry Case-Control Studies Endometriosis / physiopathology* Female Gamete Intrafallopian Transfer* / methods Humans Logistic Models Multivariate Analysis Pregnancy Pregnancy Outcome Pregnancy Rate Retrospective Studies |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Effect of oral and parenteral administration of metanil yellow on some hepatic and intestinal bioche...
Next Document: Establishment of human tubal epithelial cells for coculture in an IVF program.