Document Detail


The influence of cryopreservation on changes in diameter and compliance of allografts in an animal experimental model.
MedLine Citation:
PMID:  16564709     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: The purpose of this study was to analyze the influence of cryopreservation on changes in diameter and compliance of allografts. METHODS: Sixty aortic allografts implanted in situ in rats were analyzed. The animals were divided into four groups that received fresh or cryopreserved isogenic (Lewis to Lewis) grafts, or fresh or cryopreserved allogenic (Lewis to DA) grafts, respectively. The diameter and compliance of the grafts were then visually evaluated with the digital video camera recorder after 15, 30, 60, 90 and 120 days. RESULTS: Gradual increase in diameter and decrease in compliance in case of all allogenic and cryopreserved isogenic grafts were observed. The observed changes in cryopreserved grafts were smaller when compared with fresh grafts, however, the differences did not reach statistical significance. CONCLUSION: Cryo preservation does not protect allografts from stiffening and dilatation.
Authors:
M Gabriel; K Wachal; L Dzieciuchowicz; K Pawlaczyk; Z Krasiński; G Oszkinis
Related Documents :
7676499 - Experimental orthotopic corneal xenotransplantation in the rat. mechanisms of graft rej...
23050779 - Resveratrol supplementation influences bone properties in the tibia of hindlimb-suspend...
16641459 - Nebulized amphotericin b combined with intravenous amphotericin b in rats with severe i...
17700169 - Nitrosative stress and corneal transplant endothelial cell death during acute graft rej...
15984629 - An outbreak of rat mite dermatitis in an animal research facility.
8179379 - Donor-specific immune response after aortic valve allografting in the rat.
8138799 - Temporal evolution and spatial distribution of the diffusion constant of water in rat b...
194449 - Effects of acth and dexamethasone on the zona glomerulosa of the rat adrenal cortex: an...
8233039 - Amygdala kindling rate is altered in rats with a deficit in the responsiveness of the h...
Publication Detail:
Type:  Journal Article     Date:  2006-03-29
Journal Detail:
Title:  European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery     Volume:  32     ISSN:  1078-5884     ISO Abbreviation:  Eur J Vasc Endovasc Surg     Publication Date:  2006 Aug 
Date Detail:
Created Date:  2006-07-31     Completed Date:  2006-09-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9512728     Medline TA:  Eur J Vasc Endovasc Surg     Country:  England    
Other Details:
Languages:  eng     Pagination:  169-75     Citation Subset:  IM    
Affiliation:
Department of Vascular Surgery, University of Medical Science, Poznan, Poland. mgabriel@pro.onet.pl
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Animals
Aorta, Abdominal / metabolism,  pathology*,  transplantation
Cell Nucleus / metabolism
Cell Proliferation
Compliance*
Cryopreservation*
Fibroblasts / metabolism
Macrophages / metabolism
Male
Models, Animal
Myocytes, Smooth Muscle / metabolism
Rats
T-Lymphocytes / metabolism
Transplantation, Homologous
Tunica Intima / metabolism,  pathology
Tunica Media / metabolism,  pathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Phylogeny of sharks of the family Triakidae (Carcharhiniformes) and its implications for the evoluti...
Next Document:  Duplex guided balloon angioplasty of failing infrainguinal bypass grafts.