Document Detail


The influence of competitive flow on graft patency.
MedLine Citation:
PMID:  1388175     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
To evaluate the effects of competitive flow, bilateral aorto-iliac ePTFE grafts, 10 cm in length and with an internal diameter of 6 mm, were placed in ten mongrel dogs. On one side the external iliac artery was ligated (the control side); on the opposite side (the experimental side) flow continued through the native aorto-iliac system, as well as the graft, to allow a situation of competitive flow. Flow measurements showed the experimental graft carried 38.6% of the total blood flow going to the ipsilateral external iliac artery. After 30 days the grafts were exposed and patency and flow were evaluated by Doppler ultrasound. The control side showed 60% patency; all of the grafts on the experimental side were occluded. In addition, complete endothelial healing was observed at the occluded ostia of all experimental grafts. We conclude that competitive flow does influence graft patency and that graft thrombosis appears to be a relatively early phenomenon, as evidenced by the endothelial healing which occurred.
Authors:
R S Juleff; O W Brown; M M McKain; J L Glover; P J Bendick
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Journal of cardiovascular surgery     Volume:  33     ISSN:  0021-9509     ISO Abbreviation:  J Cardiovasc Surg (Torino)     Publication Date:    1992 Jul-Aug
Date Detail:
Created Date:  1992-10-22     Completed Date:  1992-10-22     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0066127     Medline TA:  J Cardiovasc Surg (Torino)     Country:  ITALY    
Other Details:
Languages:  eng     Pagination:  415-9     Citation Subset:  IM    
Affiliation:
Department of Surgery, William Beaumont Hospital, Royal Oak, Michigan.
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MeSH Terms
Descriptor/Qualifier:
Animals
Aorta, Abdominal / physiology,  surgery,  ultrasonography
Blood Vessel Prosthesis*
Dogs
Graft Occlusion, Vascular / physiopathology,  ultrasonography
Iliac Artery / physiology,  surgery,  ultrasonography
Ligation
Polytetrafluoroethylene
Regional Blood Flow / physiology
Rheology
Vascular Patency / physiology*
Chemical
Reg. No./Substance:
9002-84-0/Polytetrafluoroethylene

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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