Document Detail


The influence of changes in the size of ischemic region on ST-segment potential distribution in isolated canine hearts.
MedLine Citation:
PMID:  3723777     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In order to investigate how a change in the size of a ischemic region is reflected in ST-segment mapping studies, we produced two different sizes of ischemic regions by occluding proximal or distal portions of the left circumflex artery for five minutes, using ten isolated canine heart preparations. We examined the relationship between the geometry of the ischemic region and ST-segment potential distribution on the epicardial surface and that in the "precordium", in which the heart was suspended. The extent of the ischemic region was reflected differently on epicardial and "precordial" sites, in that the magnitude of epicardial ST-segment elevation decreased (p less than 0.001) while the "precordial" one increased (p less than 0.01). In the epicardium the degree of ST-segment elevation was almost uniform over the ischemic region, whereas in the "precordium" it was maximal at sites overlying the center of the ischemic region and progressively decreased approaching the periphery. However, frequent occurrence of intraventricular conduction disturbance was observed near the center of the ischemic region. As a result, the magnitude of epicardial ST-segment elevation near the center became larger than in the periphery. These results suggest that the classical solid angle theory provides a useful approximation of the ST-segment deflection in very acute ischemic phase, until development of the intraventricular conduction delay.
Authors:
H Kyono; K Maehara; Y Maruyama; Y Shimizu; S Kitaoka; Y Ishiki; S Yoshikata; E Ino-Oka; T Takishima
Related Documents :
18086137 - Ulnar artery as access site for cardiac catheterization: anatomical considerations.
12594687 - Evaluation of a spasmolytic cocktail to prevent radial artery spasm during coronary pro...
4052277 - Coronary anatomy in patients with various manifestations of three vessel coronary arter...
10642927 - Evaluation of adjunctive intracoronary administration of acetylcholine following intrav...
15657227 - Dilated coronary arterial lesions in the late period after kawasaki disease.
8897327 - Effect of polytetrafluoroethylene covering of palmaz stents on the development of intim...
Publication Detail:
Type:  In Vitro; Journal Article    
Journal Detail:
Title:  Japanese circulation journal     Volume:  50     ISSN:  0047-1828     ISO Abbreviation:  Jpn. Circ. J.     Publication Date:  1986 Feb 
Date Detail:
Created Date:  1986-08-06     Completed Date:  1986-08-06     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7806868     Medline TA:  Jpn Circ J     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  147-60     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Animals
Dogs
Electrocardiography*
Electrodes
Heart Conduction System / physiology*
Myocardial Infarction / pathology,  physiopathology*
Myocardium / pathology
Organ Size
Pericardium / physiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  How well does the activated partial thromboplastin time predict postoperative hemorrhage?
Next Document:  Evaluation of clinical factors involved in onset of myocardial infarction.