Document Detail

The influence of breathing mechanics on the development of the slow component of O2 uptake.
MedLine Citation:
PMID:  20619361     Owner:  NLM     Status:  MEDLINE    
We examined the influence of operational lung volumes and mean inspiratory flow on the amplitude of the slow component of O₂uptake (V(O)₂(SC) ) during constant-load cycling performed below and above the respiratory compensation threshold (RCT) in young (24±1yr), healthy individuals (n=10). Subjects demonstrated a significantly greater rise in expiratory reserve volume (ERV) and mean inspiratory flow over the V(O)₂(SC) period during exercise performed above compared with below the RCT (P<0.05). Inspiratory reserve volume (IRV) was, on average, smaller for trials performed above relative to below the RCT (P<0.05). The difference in the magnitudes of change in ERV and mean inspiratory flow, but not IRV, were positively correlated with the increase in V(O)₂(SC) amplitude between work rates (R(2)=0.86, P<0.01). These findings suggest that dynamic hyperinflation and mean inspiratory flow (by increasing inspiratory resistive work) contribute to the development of the V(O)₂(SC') , particularly when exercise is performed above the RCT.
Troy J Cross; Norman R Morris; Luke J Haseler; Donald A Schneider; Surendran Sabapathy
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2010-07-07
Journal Detail:
Title:  Respiratory physiology & neurobiology     Volume:  173     ISSN:  1878-1519     ISO Abbreviation:  Respir Physiol Neurobiol     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2010-09-13     Completed Date:  2010-12-28     Revised Date:  2011-01-13    
Medline Journal Info:
Nlm Unique ID:  101140022     Medline TA:  Respir Physiol Neurobiol     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  125-31     Citation Subset:  IM    
Copyright Information:
Copyright 2010 Elsevier B.V. All rights reserved.
School of Physiotherapy and Exercise Science, Gold Coast campus, Griffith University, Gold Coast, Queensland 4222, Australia.
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MeSH Terms
Exercise / physiology
Expiratory Reserve Volume / physiology
Lung Volume Measurements / methods
Oxygen / metabolism*
Respiratory Mechanics / physiology*
Respiratory Muscles / metabolism*
Rest / physiology
Work of Breathing / physiology
Young Adult
Reg. No./Substance:

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