Document Detail

The influence of birthweight on arterial blood pressure of children.
MedLine Citation:
PMID:  20116146     Owner:  NLM     Status:  MEDLINE    
BACKGROUND & AIMS: This study examined the relationship between birthweight and blood pressure in childhood. METHODS: Prospective cohort study involving 472 Brazilian children ranging in age from 5 to 8 years. Birthweight, systolic blood pressure (SBP), diastolic blood pressure (DBP), body mass index (BMI), total cholesterol and fractions (LDL-c, HDL-c), and triglycerides were determined. Total cholesterol, LDL-c, HDL-c, and triglycerides were assessed by automated enzymatic methods. Blood pressure was measured with the HDI/Pulse Wave CR-2000 equipment. Multiple regression models were used to investigate the relationship between birthweight and SBP and DBP, controlling for the following variables: gender, age, BMI, total cholesterol, triglycerides, per capita income, and maternal education. RESULTS: When adjusting for gender and BMI, we found a systolic blood pressure increase of 2.9 (95% CI=-5.33 to -0.56) mmHg per kilogram birthweight reduction. The unadjusted association was insignificant. CONCLUSION: Our data suggest that low birthweight is one of the factors contributing to blood pressure elevation at early ages. A way to prevent these diseases is by implementing public policies focused on good nutrition and adequate prenatal care for pregnant women.
Joilane A Pereira; Patricia H C Rondó; Jesuana O Lemos; José Maria Pacheco de Souza; Raimunda Sheyla C Dias
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2010-01-29
Journal Detail:
Title:  Clinical nutrition (Edinburgh, Scotland)     Volume:  29     ISSN:  1532-1983     ISO Abbreviation:  Clin Nutr     Publication Date:  2010 Jun 
Date Detail:
Created Date:  2010-06-07     Completed Date:  2010-09-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8309603     Medline TA:  Clin Nutr     Country:  England    
Other Details:
Languages:  eng     Pagination:  337-40     Citation Subset:  IM    
Copyright Information:
Copyright 2010 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism. All rights reserved.
Department of Nutrition, School of Public Health, University of São Paulo, Avenida Dr Arnaldo 715, São Paulo, SP, CEP-01246-904, Brazil.
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MeSH Terms
Age of Onset
Birth Weight*
Blood Pressure*
Body Mass Index
Child, Preschool
Cholesterol / blood
Cohort Studies
Follow-Up Studies
Hypertension / epidemiology,  prevention & control
Regression Analysis
Risk Factors
Sex Characteristics
Socioeconomic Factors
Triglycerides / blood
Reg. No./Substance:
0/Triglycerides; 57-88-5/Cholesterol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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