Document Detail


The influence of birthweight on arterial blood pressure of children.
MedLine Citation:
PMID:  20116146     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND & AIMS: This study examined the relationship between birthweight and blood pressure in childhood. METHODS: Prospective cohort study involving 472 Brazilian children ranging in age from 5 to 8 years. Birthweight, systolic blood pressure (SBP), diastolic blood pressure (DBP), body mass index (BMI), total cholesterol and fractions (LDL-c, HDL-c), and triglycerides were determined. Total cholesterol, LDL-c, HDL-c, and triglycerides were assessed by automated enzymatic methods. Blood pressure was measured with the HDI/Pulse Wave CR-2000 equipment. Multiple regression models were used to investigate the relationship between birthweight and SBP and DBP, controlling for the following variables: gender, age, BMI, total cholesterol, triglycerides, per capita income, and maternal education. RESULTS: When adjusting for gender and BMI, we found a systolic blood pressure increase of 2.9 (95% CI=-5.33 to -0.56) mmHg per kilogram birthweight reduction. The unadjusted association was insignificant. CONCLUSION: Our data suggest that low birthweight is one of the factors contributing to blood pressure elevation at early ages. A way to prevent these diseases is by implementing public policies focused on good nutrition and adequate prenatal care for pregnant women.
Authors:
Joilane A Pereira; Patricia H C Rondó; Jesuana O Lemos; José Maria Pacheco de Souza; Raimunda Sheyla C Dias
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2010-01-29
Journal Detail:
Title:  Clinical nutrition (Edinburgh, Scotland)     Volume:  29     ISSN:  1532-1983     ISO Abbreviation:  Clin Nutr     Publication Date:  2010 Jun 
Date Detail:
Created Date:  2010-06-07     Completed Date:  2010-09-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8309603     Medline TA:  Clin Nutr     Country:  England    
Other Details:
Languages:  eng     Pagination:  337-40     Citation Subset:  IM    
Copyright Information:
Copyright 2010 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism. All rights reserved.
Affiliation:
Department of Nutrition, School of Public Health, University of São Paulo, Avenida Dr Arnaldo 715, São Paulo, SP, CEP-01246-904, Brazil.
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MeSH Terms
Descriptor/Qualifier:
Age of Onset
Aging
Birth Weight*
Blood Pressure*
Body Mass Index
Child
Child, Preschool
Cholesterol / blood
Cohort Studies
Female
Follow-Up Studies
Humans
Hypertension / epidemiology,  prevention & control
Male
Prevalence
Regression Analysis
Risk Factors
Sex Characteristics
Socioeconomic Factors
Triglycerides / blood
Chemical
Reg. No./Substance:
0/Triglycerides; 57-88-5/Cholesterol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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