| The influence of atherosclerosis and plasma D-dimer concentration in patients with a functioning arteriovenous fistula for maintenance hemodialysis. | |
| | |
MedLine Citation:
|
PMID: 18228158 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
OBJECTIVE: The aim of this study was to deduce the influence of atherosclerosis and plasma D-dimer concentration on the functioning of arteriovenous fistulae for hemodialysis. METHODS: The study was organized as a prospective and non-randomized investigation in the "Kragujevac" Clinical Center. The 81 examined patients, 49 (60.5%) males and 32 (39.5%) females, were divided into a group (n = 36) requiring several attempts to create arteriovenous fistulae for hemodialysis and a group (n = 45) with no complications of arteriovenous fistulae for hemodialysis. The demographic structure, etiology of renal disease, biochemical parameters and concentration of D-dimer were analyzed at the beginning of the study and 1 year later, as well as the existence of tissue calcification and Duplex ultrasound parameters of the carotid artery. RESULTS: The patients with arteriovenous fistulae complications were significantly older (58.4 +/- 12.9 vs. 52.3 +/- 11.6 years; P = 0.026). High venous pressure (98.6 +/- 29.98 vs. 80 +/- 33.57 mmHg; P = 0.005) and soft-tissue calcification (P = 0.03) were correlated with the occurrence of arteriovenous fistula complications. The greatest risk for failure of fistula was within the first month after creation of the anastomosis (failure rate was 0.235). The hemoglobin concentration (89 +/- 14.0 vs. 96.6 +/- 17.7 g/l; P = 0.048) was lower, and concentration of D-dimer at the end of the study was higher (219.56 +/- 193.05 vs. 332.03 +/- 149.48; P = 0.012) in patients with vascular access complications. By Cox regression analysis, the concentration of fibrin D-dimer at the end of the study was shown to be a significant predictor of fistula survival (beta = 0.002; P = 0.006). CONCLUSIONS: Complications of arteriovenous fistulae were more often recorded in older patients. The greatest risk for fistula functioning was within the first month after creation of the anastomosis. Vein pressure and anemia were important indicators of arteriovenous fistula complications. D-dimer was a significant marker of arteriovenous fistula thrombosis. |
| | |
Authors:
|
Radojica V Stolic; Goran Z Trajkovic; Vladan M Peric; Aleksandar N Jovanovic; Snezana R Markovic; Sasa R Sovtic; Gordana Dj Subaric-Gorgieva |
Related Documents
:
|
15574228 - Intrinsic arteriovenous malformation of the trigeminal nerve in a patient with trigemin... 7985568 - Vein of galen aneurysms: a review and current perspective. 1924848 - Embolization of extensive facial arteriovenous malformation via the orbital branches of... 3655888 - Surgical approaches to trigonal arteriovenous malformations. 7621648 - Saline contrast and colour doppler transoesophageal echocardiography in detecting a pat... 1452348 - Lack of vessel wall elastolysis in human invasive pulmonary aspergillosis. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: International urology and nephrology Volume: 40 ISSN: 0301-1623 ISO Abbreviation: Int Urol Nephrol Publication Date: 2008 |
Date Detail:
|
Created Date: 2008-08-14 Completed Date: 2008-09-30 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0262521 Medline TA: Int Urol Nephrol Country: Hungary |
Other Details:
|
Languages: eng Pagination: 503-8 Citation Subset: IM |
Affiliation:
|
Faculty of Medicine, University of Pristina, Anri Dinana bb, Kosovska Mitrovica 38220, Serbia. radsto@ptt.yu |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Age Factors Aged Anemia / epidemiology Arteriovenous Shunt, Surgical Atherosclerosis / blood, epidemiology* Carotid Arteries / ultrasonography Comorbidity Female Fibrin Fibrinogen Degradation Products / analysis* Humans Kidney Failure, Chronic / epidemiology* Male Middle Aged Renal Dialysis Smoking / epidemiology Treatment Failure Ultrasonography, Doppler |
| Chemical | |
Reg. No./Substance:
|
0/Fibrin Fibrinogen Degradation Products; 0/fibrin fragment D |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Renal geology (quantitative renal stone analysis) by 'Fourier transform infrared spectroscopy'.
Next Document: Structural co-evolution of viruses and cells in the primordial world.