Document Detail

The influence of ascending aortic atherosclerosis on the long-term survival after CABG.
MedLine Citation:
PMID:  16126401     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: Ascending aortic atherosclerosis is a risk factor for perioperative morbidity and mortality in coronary surgery. It was the aim of our study to determine the role of atherosclerosis of the ascending aorta and other factors for the survival rate during long-term follow-up after CABG. METHODS: From 500 out of 580 CABG patients (aged 67 (33-85) years, 77% male), who underwent intraoperative epiaortic ultrasound for assessment of ascending aortic wall thickness, a complete follow up regarding long-term survival was achieved. The median follow-up time was 55 (1-78) months. RESULTS: 53/500 (11%) patients died within the follow-up period, and the cumulative survival rate was 95, 90, and 84% after 1, 3, and 5 years, respectively (including hospital deaths). A significantly lower long-term survival was present in patients with: an age of 70 years or more (P<0.001), COPD (P=0.005), preoperative elevated serum creatinine of >1.2mg/dl (P=0.007), preoperative LVEF <40% (P=0.033), ascending aortic wall thickness of 4mm or more (P=0.001), carotid artery disease (P<0.001), peripheral vascular disease (P<0.001), and acute operation (P=0.009). Multivariate analysis revealed carotid artery disease, LVEF <40%, peripheral vascular disease, and advanced age to be independent risk factors. CONCLUSION: Patients with ascending aortic atherosclerosis are at risk for a decreased long-term survival after CABG. Besides, preoperative elevated serum creatinine, COPD, carotid artery disease, LVEF <40%, peripheral vascular disease, and advanced age are risk factors for a decreased long-term survival after CABG.
Thomas Schachner; Anne Zimmer; Georg Nagele; Herbert Hangler; Günther Laufer; Johannes Bonatti
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery     Volume:  28     ISSN:  1010-7940     ISO Abbreviation:  Eur J Cardiothorac Surg     Publication Date:  2005 Oct 
Date Detail:
Created Date:  2005-09-23     Completed Date:  2006-03-02     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8804069     Medline TA:  Eur J Cardiothorac Surg     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  558-62     Citation Subset:  IM    
Department of Cardiac Surgery, Innsbruck Medical University, Innsbruck 6020, Austria.
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MeSH Terms
Age Factors
Aged, 80 and over
Aorta / ultrasonography
Aortic Diseases / mortality*,  ultrasonography
Arteriosclerosis / mortality*,  ultrasonography
Carotid Artery Diseases / mortality
Coronary Artery Bypass / methods,  mortality*
Creatinine / blood
Middle Aged
Peripheral Vascular Diseases / mortality
Preoperative Care
Prospective Studies
Pulmonary Disease, Chronic Obstructive / mortality
Risk Factors
Stroke Volume / physiology
Survival Analysis
Reg. No./Substance:

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