Document Detail

The influence of ambulatory blood pressure profile on global and regional functions of the left and the right ventricles in orderly treated hypertensive patients.
MedLine Citation:
PMID:  18279401     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: The association between nondipping profile and adverse cardiovascular outcome is still controversial. Tissue Doppler imaging (TDI), a new and useful addition to standard echocardiographic imaging techniques, permits a quantitative assessment of both global and regional function and timing of myocardial velocities. In this study, we aimed to assess whether a reduced nocturnal fall in blood pressure (BP) in orderly treated hypertensive patients with satisfactory BP control is related to more prominent structural and functional alterations of the ventricles. METHOD AND RESULTS: Sixty-nine hypertensive patients with adequate BP control were divided into two groups with respect to ambulatory BP profiles as dippers and nondippers. In addition to conventional echocardiographic parameters, in septal and lateral segments of left ventricle and free wall of right ventricle, peak systolic velocity (Sm), early (Em), and late (Am) diastolic velocities, isovolumic contraction time (ICTm), isovolumic relaxation time (IRTm), and ejection times (ETm) were measured, and modified myocardial performance index (MPIm) was calculated. Left ventricular (LV) and atrial dimensions, ejection fraction, transmitral early to late diastolic flow ratio, LV mass index, and LV hypertrophy ratio did not differ between groups. Both regional and mean LV Sm, Em/Am, MPIm and right ventricular Sm and MPIm were similar in both groups. CONCLUSION: In treated hypertensive patients with satisfactory BP control, there was no significant difference in cardiac structural and functional abnormalities among dipper and nondipper subjects.
Gulizar Sokmen; Abdullah Sokmen; Ekrem Aksu; Sedat Koroglu; Arif Suner; Cemal Tuncer
Publication Detail:
Type:  Journal Article     Date:  2008-02-12
Journal Detail:
Title:  Echocardiography (Mount Kisco, N.Y.)     Volume:  25     ISSN:  0742-2822     ISO Abbreviation:  Echocardiography     Publication Date:  2008 May 
Date Detail:
Created Date:  2008-05-02     Completed Date:  2008-09-19     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8511187     Medline TA:  Echocardiography     Country:  United States    
Other Details:
Languages:  eng     Pagination:  465-72     Citation Subset:  IM    
Cardiology Department, Faculty of Medicine, Kahramanmaras Sutcu Imam University, Kahramanmaras, Turkey.
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MeSH Terms
Blood Pressure Monitoring, Ambulatory*
Chi-Square Distribution
Circadian Rhythm
Echocardiography, Doppler*
Hypertension / drug therapy,  physiopathology,  ultrasonography*
Middle Aged
Ventricular Dysfunction, Left / physiopathology,  ultrasonography*
Ventricular Dysfunction, Right / physiopathology,  ultrasonography*

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