Document Detail

The influence of ambulatory blood pressure profile on left ventricular geometry.
MedLine Citation:
PMID:  14717714     Owner:  NLM     Status:  MEDLINE    
Besides causing a hypertrophy in the left ventricle, hypertension results in a change in the geometry of the left ventricle. The blood pressure, which does not decrease enough during the night, leads to structural changes in the left ventricle. In this study, the influence of 24-hour blood pressure profile on the left ventricular geometry was examined. Ambulatory blood pressure monitoring was applied to 60 patients with mild to moderate hypertension who had never been treated and standard echocardiographic evaluation was conducted thereafter. The patients were divided into two groups with respect to the ambulatory blood pressure profiles: the patients whose night blood pressure levels decreased by more than 10% compared to their daytime blood pressure levels (dipper) and those whose levels did not decrease that much (nondipper). The left ventricle mass index and the relative wall thickness of the patients were calculated. With respect to the left ventricle geometry, mass index and relative wall thickness of the patients were determined as: having normal geometry, concentric remodeling, eccentric hypertrophy, and concentric hypertrophy. Age, gender, systolic, and diastolic blood pressure were similar within the dipper and nondipper groups. Normal geometry, concentric remodeling, and concentric hypertrophy ratios were similar in both groups. Eccentric hypertrophy was higher in the nondipper group compared to the dipper group (42.9% vs 6.3%, P < 0.03). Patients with mild to moderate hypertension, whose blood pressure does not decrease enough, develop eccentric hypertrophy.
Bahattin Balci; Ozcan Yilmaz; Osman Yesildag
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Echocardiography (Mount Kisco, N.Y.)     Volume:  21     ISSN:  0742-2822     ISO Abbreviation:  Echocardiography     Publication Date:  2004 Jan 
Date Detail:
Created Date:  2004-01-13     Completed Date:  2004-07-02     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8511187     Medline TA:  Echocardiography     Country:  United States    
Other Details:
Languages:  eng     Pagination:  7-10     Citation Subset:  IM    
Department of Cardiology, Ondokuz Mayis University, 55060 Samsun, Turkey.
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MeSH Terms
Blood Pressure Monitoring, Ambulatory
Body Mass Index
Circadian Rhythm
Hypertension / complications*,  physiopathology,  ultrasonography
Hypertrophy, Left Ventricular / etiology*,  physiopathology,  ultrasonography
Middle Aged
Ventricular Remodeling / physiology*

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