| The influence of alpha-linolenic acid (18: 3omega3) on the metabolism of gamma-linolenic acid (18: 3omega6) in the rat. | |
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MedLine Citation:
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PMID: 889767 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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1. Essential fatty acid-deficient rats were fed gamma-linolenic acid (18: 3omega6) at 2% dietary energy and alpha-linolenic acid (18: 3omega3) at 0, 1-6, 2-8 and 4-0% of the dietary energy. 2. 18: 3omega3 at 1-6% apparently inhibits the synthesis of the C20 and C22 omega6 long-chain polyunsaturated fatty acids (omega6 LC-PUFA) metabolized from 18: 3omega6. 3. However, increasing the dietary levels of 18: 3omega3 from 1-6 to 4-0% has no further influence. 4. The results suggest that dietary 18: 3omega6 is an efficent precursor for the omega6 LC-PUFA synthesis even in the presence of 18: 3omega3. |
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Authors:
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A G Hassam |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: The British journal of nutrition Volume: 38 ISSN: 0007-1145 ISO Abbreviation: Br. J. Nutr. Publication Date: 1977 Jul |
Date Detail:
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Created Date: 1977-10-28 Completed Date: 1977-10-28 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 0372547 Medline TA: Br J Nutr Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 137-40 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animal Nutritional Physiological Phenomena Animals Dietary Fats / administration & dosage Fatty Acids, Essential / metabolism Fatty Acids, Unsaturated / biosynthesis Female Glycerophosphates / metabolism Linoleic Acids / administration & dosage Linolenic Acids / metabolism* Liver / metabolism* Rats |
| Chemical | |
Reg. No./Substance:
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0/Dietary Fats; 0/Fatty Acids, Essential; 0/Fatty Acids, Unsaturated; 0/Glycerophosphates; 0/Linoleic Acids; 0/Linolenic Acids |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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