| The influence of air pollution on cardiovascular and pulmonary function and exercise capacity: Canadian Health Measures Survey (CHMS). | |
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MedLine Citation:
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PMID: 22000598 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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BACKGROUND: Air pollution has been associated with adverse cardiovascular effects. OBJECTIVE: To measure the association between air pollution, spirometry, blood pressure, and exercise capacity. METHODS: We used data from 5604 subjects collected during the Canada Health Measures Survey to test the association between air pollution measured on the day of the survey and spirometry (n=5011 subjects), blood pressure, and exercise capacity (n=3789 subjects). RESULTS: An interquartile range (IQR) increase in ozone (17.0ppb) was significantly associated with a 0.883% higher resting heart rate, a 0.718% higher systolic and 0.407% higher diastolic blood pressure, a 0.393% lower FEV(1)/FVC expressed as a percentage of predicted, and a 1.52% reduction in the aerobic fitness score (p<0.05). Resting systolic and diastolic blood pressure were approximately 0.5mmHg higher for an (IQR 4.5μg/m(3)) increase in PM(2.5) (IQR 4.5μg/m(3)) and 1mmHg higher for a 12.6ppb increase in NO(2) (IQR 12.6ppb). An increase in PM(2.5) was also associated with an approximate 0.4% decrease in percent predicted FEV(1) and FVC (p<0.05). CONCLUSION: Exposure to higher concentrations of air pollution was associated with higher resting blood pressure and lower ventilatory function. Ozone was associated with reduced exercise capacity. |
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Authors:
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Sabit Cakmak; Robert Dales; Judith Leech; Ling Liu |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-10-13 |
Journal Detail:
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Title: Environmental research Volume: - ISSN: 1096-0953 ISO Abbreviation: - Publication Date: 2011 Oct |
Date Detail:
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Created Date: 2011-10-17 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0147621 Medline TA: Environ Res Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2011 Elsevier Inc. All rights reserved. |
Affiliation:
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Biostatistics Section, Biostatistics and Epidemiology Division, Environmental Health Science & Research Bureau, Health Canada, 50 Columbine Driveway, Ottawa, ON, Canada K1A 0K9. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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