Document Detail

The influence of air pollution on cardiovascular and pulmonary function and exercise capacity: Canadian Health Measures Survey (CHMS).
MedLine Citation:
PMID:  22000598     Owner:  NLM     Status:  Publisher    
BACKGROUND: Air pollution has been associated with adverse cardiovascular effects. OBJECTIVE: To measure the association between air pollution, spirometry, blood pressure, and exercise capacity. METHODS: We used data from 5604 subjects collected during the Canada Health Measures Survey to test the association between air pollution measured on the day of the survey and spirometry (n=5011 subjects), blood pressure, and exercise capacity (n=3789 subjects). RESULTS: An interquartile range (IQR) increase in ozone (17.0ppb) was significantly associated with a 0.883% higher resting heart rate, a 0.718% higher systolic and 0.407% higher diastolic blood pressure, a 0.393% lower FEV(1)/FVC expressed as a percentage of predicted, and a 1.52% reduction in the aerobic fitness score (p<0.05). Resting systolic and diastolic blood pressure were approximately 0.5mmHg higher for an (IQR 4.5μg/m(3)) increase in PM(2.5) (IQR 4.5μg/m(3)) and 1mmHg higher for a 12.6ppb increase in NO(2) (IQR 12.6ppb). An increase in PM(2.5) was also associated with an approximate 0.4% decrease in percent predicted FEV(1) and FVC (p<0.05). CONCLUSION: Exposure to higher concentrations of air pollution was associated with higher resting blood pressure and lower ventilatory function. Ozone was associated with reduced exercise capacity.
Sabit Cakmak; Robert Dales; Judith Leech; Ling Liu
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-10-13
Journal Detail:
Title:  Environmental research     Volume:  -     ISSN:  1096-0953     ISO Abbreviation:  -     Publication Date:  2011 Oct 
Date Detail:
Created Date:  2011-10-17     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0147621     Medline TA:  Environ Res     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2011 Elsevier Inc. All rights reserved.
Biostatistics Section, Biostatistics and Epidemiology Division, Environmental Health Science & Research Bureau, Health Canada, 50 Columbine Driveway, Ottawa, ON, Canada K1A 0K9.
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