Document Detail

The influence of the acidic component of the gas-foaming porogen used in preparing an injectable porous calcium phosphate cement on its properties: acetic acid versus citric acid.
MedLine Citation:
PMID:  18161816     Owner:  NLM     Status:  MEDLINE    
In the present study, macroporous calcium phosphate cements (CPCs) were prepared using a porogen; that is, the gas-foaming technique. The objective was to investigate the influence of the acidic component of the porogen (acetic acid versus citric acid) on several properties of a specified CPC. In all of the cements prepared, the basic component of the porogen was the same, namely, NaHCO(3), and it was added to the powder phase of the cement, while the acidic component of the porogen was dissolved in the liquid phase of the cement. The cements were characterized in terms of initial setting time, porosity, crystallinity, injectability and compressive strength. Also, XRD, FTIR, and SEM techniques were employed to evaluate the phase composition, the chemical groups and the morphological aspects of the porous cements during setting. It was found that the presence of a porogen in a CPC led to significant decreases in both its initial setting time and compressive strength. A CPC made using acetic acid contained a larger amount of the apatite phase but was significantly less injectable and less porous than when citric acid was used.
Saeed Hesaraki; Ali Zamanian; Fatollah Moztarzadeh
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of biomedical materials research. Part B, Applied biomaterials     Volume:  86     ISSN:  1552-4981     ISO Abbreviation:  J. Biomed. Mater. Res. Part B Appl. Biomater.     Publication Date:  2008 Jul 
Date Detail:
Created Date:  2008-06-23     Completed Date:  2008-11-24     Revised Date:  2013-04-05    
Medline Journal Info:
Nlm Unique ID:  101234238     Medline TA:  J Biomed Mater Res B Appl Biomater     Country:  United States    
Other Details:
Languages:  eng     Pagination:  208-16     Citation Subset:  IM    
Copyright Information:
2007 Wiley Periodicals, Inc.
Ceramics Department, Materials and Energy Research Center, Karaj, Tehran 1516953715, Iran.
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MeSH Terms
Acetic Acid / chemistry*
Apatites / chemistry
Biocompatible Materials / chemistry*
Bone Cements / chemistry*
Bone Substitutes / chemistry*
Calcium Phosphates / chemistry*
Citric Acid / chemistry*
Compressive Strength
Microscopy, Electron, Scanning / methods
Models, Chemical
Models, Statistical
Spectroscopy, Fourier Transform Infrared
Time Factors
X-Ray Diffraction
Reg. No./Substance:
0/Apatites; 0/Biocompatible Materials; 0/Bone Cements; 0/Bone Substitutes; 0/Calcium Phosphates; 64-19-7/Acetic Acid; 77-92-9/Citric Acid; 97Z1WI3NDX/calcium phosphate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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