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The inflammatory process underlying atherosclerosis.
MedLine Citation:
PMID:  23339672     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Atherosclerosis is considered an inflammatory disease that starts and evolves in response to cholesterol accumulation in the arterial intima of the large and medium arteries. In recent years, new insights into innate immunity have changed our understanding of the events that initiate and drive inflammation, changing many concepts about pathogenesis of inflammatory disorders and on the susceptibility to infections. This review summarizes some of the current concepts on innate immunity and rearranges old and new data on pathogenesis in atherosclerosis to shed light on the disease with a new inflammatory view.
Authors:
M Teresa Montero-Vega
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Critical reviews in immunology     Volume:  32     ISSN:  1040-8401     ISO Abbreviation:  Crit. Rev. Immunol.     Publication Date:  2012  
Date Detail:
Created Date:  2013-01-23     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8914819     Medline TA:  Crit Rev Immunol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  373-462     Citation Subset:  IM    
Affiliation:
Department of Research in Biochemistry, Ramon y Cajal Institute for Health Research (IRYCIS), Ramon y Cajal University Hospital, Ctra. Colmenar, km 9, 28034-Madrid, Spain.
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