| The infant and hepatitis B virus infection. | |
| | |
MedLine Citation:
|
PMID: 602864 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
HBV has been shown to be responsible for a broad spectrum of disease in infants although most are asymptomatic carriers with mild transaminase elevation and unresolved hepatitis on liver biopsy. Maternal-infant transmission is responsible for most infections. Blood product infusion should become less significant. Acute maternal hepatitis in the perinatal period results in asymptomatic infant infections at rates far exceeding transmission from asymptomatic carrier mothers. Carrier mothers with the e-antigen or HBV-associated DNA polymerase transmit infection more readily than do carrier mothers without these HBV markers. The presence of maternal anti-e may be protective. Intrapartum and postpartum transmission occurs more often than transplacental infection. For this reason attempts at prophylaxis with immune serum globulin administered in the newborn period should be further evaluated. |
| | |
Authors:
|
J N Isenberg |
Related Documents
:
|
20104104 - Prevention of mother-to-child transmission of hiv-1 using highly active antiretroviral ... 7935654 - Reduction of maternal-infant transmission of human immunodeficiency virus type 1 with z... 21165814 - Life-threatening hypernatremic dehydration in a 7-week-old exclusively breastfed infant... 9593004 - Mother-to-infant transmission of gb virus c/hepatitis g virus: the role of high-titered... 6222654 - Obstetric management of the fetus with omphalocele or gastroschisis: a review and repor... 20609624 - Cardiovascular control during sleep in infants: implications for sudden infant death sy... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Advances in pediatrics Volume: 24 ISSN: 0065-3101 ISO Abbreviation: Adv Pediatr Publication Date: 1977 |
Date Detail:
|
Created Date: 1978-03-21 Completed Date: 1978-03-21 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 0370436 Medline TA: Adv Pediatr Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 455-63 Citation Subset: IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Female Hepatitis B* / therapy, transmission Hepatitis B Antigens Humans Infant, Newborn Infant, Newborn, Diseases* / therapy, transmission Pregnancy Pregnancy Complications, Infectious |
| Chemical | |
Reg. No./Substance:
|
0/Hepatitis B Antigens |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Arachnoid diverticula: a unitary approach to spinal cysts communicating with the subarachnoid space.
Next Document: Performance at school in children suffering of cerebral-convulsion-disease (author's transl)