Document Detail


An inexpensive servo-respirator based upon regulation of a shunt resistance.
MedLine Citation:
PMID:  3175357     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We have designed and built an inexpensive servo-respirator for use in investigations of respiratory control in small animals. The device uses a butterfly valve to alter the resistance of an outflow shunt from a manifold that connects the animal's tracheal cannula to a pressure source. Tracheal pressure is regulated in response to a command provided by a suitably processed neural signal, often the integrated phrenic neurogram. As the valve opens, tracheal pressure approaches atmospheric; as it closes, tracheal pressure approaches the source pressure. An electronic controller circuit was developed to permit experimental procedures that include withholding volume delivery while maintaining a desired level of positive end-expiratory pressure. The device is able to track the neural command signal satisfactorily, and its performance appears to be limited primarily by the constraints applied by the respiratory system mechanics.
Authors:
J A Daubenspeck; D Pichon; K V Knuth; D Bartlett; W M St John
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Respiration physiology     Volume:  73     ISSN:  0034-5687     ISO Abbreviation:  Respir Physiol     Publication Date:  1988 Jul 
Date Detail:
Created Date:  1988-10-31     Completed Date:  1988-10-31     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0047142     Medline TA:  Respir Physiol     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  87-96     Citation Subset:  IM    
Affiliation:
Department of Physiology, Dartmouth Medical School, Hanover, NH 03756.
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MeSH Terms
Descriptor/Qualifier:
Airway Resistance
Animals
Cats
Equipment Design
Humans
Kinetics
Pressure
Pulmonary Ventilation
Respiration, Artificial*
Trachea / physiology
Ventilators, Mechanical*
Grant Support
ID/Acronym/Agency:
HL19827/HL/NHLBI NIH HHS; HL26091/HL/NHLBI NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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