Document Detail

An inexpensive servo-respirator based upon regulation of a shunt resistance.
MedLine Citation:
PMID:  3175357     Owner:  NLM     Status:  MEDLINE    
We have designed and built an inexpensive servo-respirator for use in investigations of respiratory control in small animals. The device uses a butterfly valve to alter the resistance of an outflow shunt from a manifold that connects the animal's tracheal cannula to a pressure source. Tracheal pressure is regulated in response to a command provided by a suitably processed neural signal, often the integrated phrenic neurogram. As the valve opens, tracheal pressure approaches atmospheric; as it closes, tracheal pressure approaches the source pressure. An electronic controller circuit was developed to permit experimental procedures that include withholding volume delivery while maintaining a desired level of positive end-expiratory pressure. The device is able to track the neural command signal satisfactorily, and its performance appears to be limited primarily by the constraints applied by the respiratory system mechanics.
J A Daubenspeck; D Pichon; K V Knuth; D Bartlett; W M St John
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Respiration physiology     Volume:  73     ISSN:  0034-5687     ISO Abbreviation:  Respir Physiol     Publication Date:  1988 Jul 
Date Detail:
Created Date:  1988-10-31     Completed Date:  1988-10-31     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0047142     Medline TA:  Respir Physiol     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  87-96     Citation Subset:  IM    
Department of Physiology, Dartmouth Medical School, Hanover, NH 03756.
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MeSH Terms
Airway Resistance
Equipment Design
Pulmonary Ventilation
Respiration, Artificial*
Trachea / physiology
Ventilators, Mechanical*
Grant Support

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