| The induction and transplantation of hepatomas in Wistar and BD IX rats. | |
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MedLine Citation:
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PMID: 106117 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Hepatomas were induced by feeding rats laboratory chow containing 0,6375 g of 3'-methyl-4-dimethylaminoazobenzene per kg for 3 to 5 months. DAB-1 was a hepatoma induced in randomly bred Wistar rats and was transplanted for 3 years after which it failed to grow in vivo but not in vitro. DAB-2 and DAB-3 are new transplantable hepatoma lines established in highly inbred DBIX rats. DAB-3 has a metaplastic morphology showing, inter alia, goblet cells, cartilagenous areas, duct-like structures and glandular follicles. This is unlike DAB-1 and DAB-2 which showed poorly differentiated trabecular or anaplastic carcinomatous patterns. |
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Authors:
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C F Albrecht; J D Dijkstra |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of the South African Veterinary Association Volume: 49 ISSN: 1019-9128 ISO Abbreviation: J S Afr Vet Assoc Publication Date: 1978 Sep |
Date Detail:
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Created Date: 1979-05-16 Completed Date: 1979-05-16 Revised Date: 2003-11-14 |
Medline Journal Info:
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Nlm Unique ID: 7503122 Medline TA: J S Afr Vet Assoc Country: SOUTH AFRICA |
Other Details:
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Languages: eng Pagination: 247-8 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Liver Neoplasms, Experimental / chemically induced* Male Neoplasm Transplantation / veterinary* Rats Rats, Inbred Strains p-Dimethylaminoazobenzene |
| Chemical | |
Reg. No./Substance:
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60-11-7/p-Dimethylaminoazobenzene |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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