| Levodopa/carbidopa/entacapone-induced acute Pisa syndrome in a Parkinson's disease patient. | |
MedLine Citation:
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PMID: 18814889 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Pisa syndrome (PS) is a dystonic lateroflexion of the trunk with a postural disturbance resembling the leaning tower of Pisa. Initially reported as a side effect related to antipsychotic therapy, this original dystonic posture is also manifested in neurodegenerative disorders such as Alzheimer's disease and multiple system atrophy, or in rare idiopathic cases. Recent observations have described the onset of PS with subchronic course in patients affected by Parkinson's disease (PD). Here, we report on the acute development of PS in a parkinsonian patient during treatment with entacapone/levodopa/carbidopa combination. This case illustrates how, in contrast to previously well-known chronic/subchronic forms, this axial dystonic posture may occur in PD as an acute onset reversible type, related to levodopa treatment. |
Authors:
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Paolo Solla; Antonino Cannas; Socrate Congia; Gianluca Floris; Rosa Aste; Paolo Tacconi; Maria Giovanna Marrosu |
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Publication Detail:
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Type: Case Reports; Journal Article Date: 2008-09-23 |
Journal Detail:
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Title: Journal of the neurological sciences Volume: 275 ISSN: 0022-510X ISO Abbreviation: J. Neurol. Sci. Publication Date: 2008 Dec |
Date Detail:
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Created Date: 2008-11-17 Completed Date: 2009-04-09 Revised Date: 2013-11-25 |
Medline Journal Info:
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Nlm Unique ID: 0375403 Medline TA: J Neurol Sci Country: Netherlands |
Other Details:
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Languages: eng Pagination: 154-6 Citation Subset: IM |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Antiparkinson Agents
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adverse effects* Carbidopa / adverse effects Catechols / adverse effects Dystonic Disorders / chemically induced*, radionuclide imaging Humans Levodopa / adverse effects Male Middle Aged Nitriles / adverse effects Parkinson Disease / drug therapy, radionuclide imaging Tomography, Emission-Computed, Single-Photon / methods Tropanes / diagnostic use |
| Chemical | |
Reg. No./Substance:
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0/Antiparkinson Agents; 0/Catechols; 0/Nitriles; 0/Tropanes; 155797-99-2/2-carbomethoxy-8-(3-fluoropropyl)-3-(4-iodophenyl)tropane; 46627O600J/Levodopa; 4975G9NM6T/entacapone; MNX7R8C5VO/Carbidopa |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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