Document Detail


Quinupristin/dalfopristin-induced Sweet's syndrome.
MedLine Citation:
PMID:  14619389     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Quinupristin/Dalfopristin is a new combination of streptogramin antibiotics designed specifically to treat clinically significant infections due to Vancomycin-resistant Enterococcus Faecium. Sweet's syndrome is characterized by painful skin plaques, which is associated with dermal neutrophilic infiltration, fever and peripheral blood leukocytosis. Drug-induced Sweet's syndrome has a temporal relationship between drug ingestion, clinical presentation and the temporally-related resolution of lesions following drug withdrawal or on treatment with systemic corticosteroids. A 63-year-old woman received Quinupristin/Dalfopristin for acute pyelonephritis developed fever, arthralgia, vomiting, and painful erythematous skin plaques. A skin biopsy showed neutrophilic dermatosis, and there was rapid resolution of the symptoms and cutaneous lesions after discontinuation of Quinupristin/Dalfopristin, consistent with drug-induced Sweet's syndrome. To date, there has been no reported case of Sweet's syndrome associated with the use of Quinupristin/Dalfopristin.
Authors:
Hye Sook Choi; Hee Jin Kim; Tae Hee Lee; Sang Hoon Lee; Tae Won Lee; Chun Gyoo Ihm; Myung Jae Kim
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Korean journal of internal medicine     Volume:  18     ISSN:  1226-3303     ISO Abbreviation:  Korean J. Intern. Med.     Publication Date:  2003 Sep 
Date Detail:
Created Date:  2003-11-17     Completed Date:  2004-01-05     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  8712418     Medline TA:  Korean J Intern Med     Country:  Korea (South)    
Other Details:
Languages:  eng     Pagination:  187-90     Citation Subset:  IM    
Affiliation:
Department of Internal Medicine, School of Medicine, Kyung Hee University, Seoul, Korea.
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MeSH Terms
Descriptor/Qualifier:
Anti-Bacterial Agents / administration & dosage,  adverse effects*
Female
Humans
Middle Aged
Skin / drug effects,  pathology
Sweet Syndrome / chemically induced*,  pathology
Virginiamycin / administration & dosage,  adverse effects*,  analogs & derivatives*
Chemical
Reg. No./Substance:
0/Anti-Bacterial Agents; 11006-76-1/Virginiamycin; 112362-50-2/dalfopristin; 120138-50-3/quinupristin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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