Document Detail

The independent roles of diet and serum lipids in the 20th-century rise and decline of coronary heart disease mortality.
MedLine Citation:
PMID:  8476745     Owner:  NLM     Status:  MEDLINE    
Risk factors are causally related to coronary heart disease (CHD), but in widely varying historic, geographic, socioeconomic, and individual relationships. Serum cholesterol is only one of many risk factors that, even when considered together in prospective studies, account for well under half of the CHD incidence. It is neither primarily regulated by the diet nor significantly related to it. Many findings discordant with widespread beliefs about a causal role of the diet in CHD are reviewed. It may be concluded that dietary fats are largely not responsible for relationships of serum cholesterol to CHD, or for its 20th-century rise and decline.
R H Rosenman
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Integrative physiological and behavioral science : the official journal of the Pavlovian Society     Volume:  28     ISSN:  1053-881X     ISO Abbreviation:  Integr Physiol Behav Sci     Publication Date:    1993 Jan-Mar
Date Detail:
Created Date:  1993-05-24     Completed Date:  1993-05-24     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9105843     Medline TA:  Integr Physiol Behav Sci     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  84-98     Citation Subset:  IM    
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MeSH Terms
Coronary Disease / blood,  etiology,  mortality*
Diet / adverse effects,  trends*
Lipids / blood*
Risk Factors
Reg. No./Substance:

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