Document Detail


The incubation period of hantavirus pulmonary syndrome.
MedLine Citation:
PMID:  11304061     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In 1993 Sin Nombre virus was recognized as the cause of hantavirus pulmonary syndrome (HPS) and the deer mouse (Peromyscus maniculatus) was identified as the reservoir host. Surveillance by the Centers for Disease Control and Prevention and state health departments includes investigation to determine the likely site(s) and activities that led to infection, an environmental assessment of the home and workplace, and possibly rodent trappings at these sites. As of December 31, 1998, there were 200 confirmed cases from 30 states (43% case-fatality ratio). The national HPS case registry was examined to determine the incubation period of HPS. Review of 11 case-patients with well-defined and isolated exposure to rodents suggests that the incubation period of HPS is 9 to 33 days, with a median of 14-17 days. Case investigations allow a better understanding of the incubation time of HPS and may define high-risk behaviors that can be targeted for intervention.
Authors:
J C Young; G R Hansen; T K Graves; M P Deasy; J G Humphreys; C L Fritz; K L Gorham; A S Khan; T G Ksiazek; K B Metzger; C J Peters
Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  The American journal of tropical medicine and hygiene     Volume:  62     ISSN:  0002-9637     ISO Abbreviation:  Am. J. Trop. Med. Hyg.     Publication Date:  2000 Jun 
Date Detail:
Created Date:  2001-04-16     Completed Date:  2001-05-03     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  0370507     Medline TA:  Am J Trop Med Hyg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  714-7     Citation Subset:  AIM; IM    
Affiliation:
Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30329-4018, USA. jyoung@cdc.gov
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MeSH Terms
Descriptor/Qualifier:
Adult
Animals
Disease Reservoirs*
Environmental Exposure*
Female
Hantavirus*
Hantavirus Infections / transmission,  veterinary,  virology
Hantavirus Pulmonary Syndrome / transmission*,  virology
Housing
Humans
Male
Middle Aged
Occupational Exposure
Peromyscus / physiology,  virology*
Recreation
Registries
Rodent Diseases / virology*
Time Factors
Comments/Corrections
Comment In:
Am J Trop Med Hyg. 2001 Nov;65(5):403   [PMID:  11716089 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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