Document Detail

The incremental shuttle walking test in elderly people with chronic airflow limitation.
MedLine Citation:
PMID:  11809987     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: There is a concern that comorbidity or frailty in older people could limit the usefulness of currently available exercise tests for chronic lung disease. This study evaluated the feasibility and reproducibility of the incremental shuttle walking test (SWT) in people aged 70 years or over, compared exercise tolerance with other disability markers, and assessed whether the SWT is responsive to change after bronchodilators. METHODS: Fifty elderly patients with chronic airflow limitation (CAL) and 32 controls without airflow limitation attempted the SWT before and after combined nebulised salbutamol/ipratropium bromide. Subjects also completed the Nottingham Extended Activities of Daily Living index (NEADL) and the London Handicap score (LHS). RESULTS: Forty four subjects with CAL (88%) and 29 controls (84%) completed the SWT, including many with co-morbidities. Two week repeatability was good and the SWT was strongly associated with EADL (r=0.51, p<0.001) and LHS (r=0.43, p<0.004), but only weakly with forced expiratory volume in 1 second (FEV1) (r=0.31, p=0.05). Subjects with CAL walked a mean distance of 177.7 m compared with 243.3 m in controls (p<0.001); following bronchodilator therapy the distance walked increased in the CAL group by 13.2% (p=0.009). CONCLUSION: The SWT is a feasible and reproducible measure of exercise tolerance in elderly people with and without airflow obstruction and correlates with other markers of disability. It is sensitive to change following bronchodilation in subjects with CAL, although the change correlates less well with improvements in FEV1. Overall, these results suggest that the SWT might be an appropriate measure to assess interventions in elderly people.
C A E Dyer; S J Singh; R A Stockley; A J Sinclair; S L Hill
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Publication Detail:
Type:  Clinical Trial; Controlled Clinical Trial; Journal Article    
Journal Detail:
Title:  Thorax     Volume:  57     ISSN:  0040-6376     ISO Abbreviation:  Thorax     Publication Date:  2002 Jan 
Date Detail:
Created Date:  2002-01-25     Completed Date:  2002-02-19     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0417353     Medline TA:  Thorax     Country:  England    
Other Details:
Languages:  eng     Pagination:  34-8     Citation Subset:  IM    
Department of Geriatric Medicine, Royal United Hospital Bath NHS Trust, Bath, UK.
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MeSH Terms
Administration, Inhalation
Aged, 80 and over
Albuterol / administration & dosage,  pharmacology
Asthma / physiopathology*
Bronchodilator Agents / administration & dosage,  pharmacology
Drug Combinations
Exercise Test / drug effects*,  standards
Forced Expiratory Volume / drug effects
Ipratropium / administration & dosage,  pharmacology
Pulmonary Disease, Chronic Obstructive / diagnosis*,  physiopathology
Reproducibility of Results
Sensitivity and Specificity
Vital Capacity / drug effects
Walking / physiology
Reg. No./Substance:
0/Bronchodilator Agents; 0/Drug Combinations; 18559-94-9/Albuterol; 60205-81-4/Ipratropium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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