Document Detail

The increasing incidence of fetal echogenic congenital lung malformations: an observational study.
MedLine Citation:
PMID:  25256093     Owner:  NLM     Status:  Publisher    
OBJECTIVES: To investigate the incidence of congenital lung malformations over the past 19 years. Congenital lung malformations (CLM) are a heterogeneous group of lung abnormalities. The antenatal diagnosis is important for fetal and neonatal management but there have been no studies examining whether the reported incidence of this abnormality is constant.
METHODS: A retrospective cross-sectional study of cases identified from the Wessex Antenatally Detected Anomalies (WANDA) register 1994-2012.
RESULTS: 133 cases of CLM in 524 372 live and stillbirths were identified with all but seven identified on antenatal ultrasound. During the early registry (1994-1998) the average incidence of CLM was 1.27 per 10 000 births. By the last four years (2008-2012) this had risen to 4.15 per 10 000 births, with a progressive increase during the intervening years.
CONCLUSION: There was over a three-fold increase in the antenatally detected CLM in the Wessex region 1994-2012. Comparison with the antenatal detection of diaphragmatic hernia suggests that this is a true rise in incidence rather than an artefactual increase due to increased antenatal recognition because of improved ultrasound resolution and operator experience. These results have clinical and cost implications for practitioners of fetal medicine, neonatology and paediatric surgery services. © 2014 John Wiley & Sons, Ltd.
L J Stocker; D G Wellesley; M P Stanton; R Parasuraman; D T Howe
Related Documents :
17165843 - Characterization of chiral interactions using fluorescence anisotropy.
25353183 - The maternal environment programmes postnatal weight gain and glucose tolerance of male...
3658913 - Pseudomosaicism for trisomy 13. three case reports.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-9-25
Journal Detail:
Title:  Prenatal diagnosis     Volume:  -     ISSN:  1097-0223     ISO Abbreviation:  Prenat. Diagn.     Publication Date:  2014 Sep 
Date Detail:
Created Date:  2014-9-26     Completed Date:  -     Revised Date:  2014-9-27    
Medline Journal Info:
Nlm Unique ID:  8106540     Medline TA:  Prenat Diagn     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© 2014 John Wiley & Sons, Ltd.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Comparison of rehospitalization rates in France and the United States.
Next Document:  Magnetic resonance imaging aspects of giant-cell tumours of bone.