Document Detail


An increased ability to generate hydrogen peroxide in certain polymorphonuclear leukocytes in neonates.
MedLine Citation:
PMID:  1391277     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We performed a quantitative assay of the hydrogen peroxide generation in polymorphonuclear leukocytes using single cell analysis by flow cytometry. The study population included premature neonates (n = 10), term neonates (n = 28) and healthy adults (n = 29). The ability to generate hydrogen peroxide in neonatal polymorphonuclear leukocytes was totally reduced compared with adults, however, some polymorphonuclear leukocytes in neonates demonstrated highly accentuated hydrogen peroxide generation.
Authors:
D Ueda; Y Sakata; K Sasaki; H Azuma
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Biology of the neonate     Volume:  62     ISSN:  0006-3126     ISO Abbreviation:  Biol. Neonate     Publication Date:  1992  
Date Detail:
Created Date:  1992-11-23     Completed Date:  1992-11-23     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0247551     Medline TA:  Biol Neonate     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  63-6     Citation Subset:  IM    
Affiliation:
Department of Pediatrics, Asahikawa Medical College, Japan.
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MeSH Terms
Descriptor/Qualifier:
Adult
Flow Cytometry
Humans
Hydrogen Peroxide / blood*
Infant, Newborn / blood*
Infant, Premature / blood
Neutrophils / metabolism*
Chemical
Reg. No./Substance:
7722-84-1/Hydrogen Peroxide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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