Document Detail

The increase of femoral arterial flow by stimulating the dorsal and ventral medulla in cats.
MedLine Citation:
PMID:  8156649     Owner:  NLM     Status:  MEDLINE    
1. In chloralose-urethane anaesthetized cats, the dorsal cardiovascular reactive area (DCRA) in the parvocellular reticular nucleus dorsomedial to the facial nucleus, and the ventral cardiovascular reactive area (VCRA) ventromedial to the facial nucleus, were stimulated by microinjections of sodium glutamate (100-200 nmol) or electric current. 2. Stimulation of DCRA, with a long latency of 15-20 s, elicited a marked increase of blood flow in the contralateral femoral artery with little change to moderate increase in systemic arterial blood pressure (ABP). In the relatively dorsal portion of DCRA, however, a smaller increase of blood flow in the ipsilateral femoral artery was elicited. 3. On the other hand, stimulation of VCRA with a short latency (3-5s) evoked an increase of blood flow in both femoral arteries which was more prominent on the contralateral side. The responses were accompanied with decreases in the blood flow of other vascular beds with only a slight increase or minimal change in ABP. 4. The data suggest that DCRA and VCRA are both viscerotopically organized to alter the resistance of individual vascular beds for redistribution of blood flow.
M R Wang; C Y Chai; J S Kuo
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Clinical and experimental pharmacology & physiology     Volume:  21     ISSN:  0305-1870     ISO Abbreviation:  Clin. Exp. Pharmacol. Physiol.     Publication Date:  1994 Jan 
Date Detail:
Created Date:  1994-05-17     Completed Date:  1994-05-17     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0425076     Medline TA:  Clin Exp Pharmacol Physiol     Country:  AUSTRALIA    
Other Details:
Languages:  eng     Pagination:  21-9     Citation Subset:  IM; S    
Aerospace Medical Center, Air Force General Hospital, Taipei, Taiwan, Republic of China.
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MeSH Terms
Blood Flow Velocity / drug effects
Blood Pressure
Electric Stimulation
Femoral Artery / drug effects,  physiology*
Heart Rate
Medulla Oblongata / physiology*
Regional Blood Flow / drug effects
Sodium Glutamate / pharmacology
Reg. No./Substance:
142-47-2/Sodium Glutamate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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