Document Detail

The incidence and prognosis of unrecognized myocardial infarction in the Honolulu, Hawaii, Heart Program.
MedLine Citation:
PMID:  2742427     Owner:  NLM     Status:  MEDLINE    
The incidence of clinically unrecognized myocardial infarctions among 7331 Japanese-American men in Hawaii, aged 45 to 68 years and free of coronary heart disease at entry, was studied on the basis of electrocardiographic changes between successive examinations during 6 years of follow-up. The proportion of asymptomatic myocardial infarction accounted for 33% of transmural (Q-wave) myocardial infarctions identified by temporal changes on electrocardiogram and 22% of all nonfatal infarctions ascertained by either repeated examinations or hospital surveillance. The 10-year prognosis of unrecognized infarction, in terms of mortality from all causes, cardiovascular disease, and coronary heart disease, was worse (with risk ratios of 1.5 to 1.7) than that of recognized infarction, even after adjusting for age and other possible determinants, although the differences were not statistically significant. These findings suggest that regular health check-ups with an electrocardiogram would be important to detect asymptomatic myocardial infarction and to increase the opportunity of taking secondary preventive measures. However, the conclusion should await further studies based on intervention trials to determine the comparative effects of the secondary prevention on the prognosis of clinically recognized vs unrecognized infarction.
K Yano; C J MacLean
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Archives of internal medicine     Volume:  149     ISSN:  0003-9926     ISO Abbreviation:  Arch. Intern. Med.     Publication Date:  1989 Jul 
Date Detail:
Created Date:  1989-08-10     Completed Date:  1989-08-10     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0372440     Medline TA:  Arch Intern Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1528-32     Citation Subset:  AIM; IM    
Honolulu, Hawaii, Heart Program, Kuakini Medical Center 98817.
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MeSH Terms
Asian Americans
Epidemiologic Methods
Follow-Up Studies
Japan / ethnology
Middle Aged
Myocardial Infarction / epidemiology*,  ethnology,  mortality,  physiopathology
Prospective Studies
Grant Support
Comment In:
Arch Intern Med. 1990 Jun;150(6):1350   [PMID:  2353871 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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