Document Detail

The incidence and distribution of oral lesions in patients with Darier's disease.
MedLine Citation:
PMID:  1931295     Owner:  NLM     Status:  MEDLINE    
Darier's disease is an uncommon autosomal dominant genodermatosis that may be accompanied by oral lesions. The incidence and distribution of oral manifestations was studied in 24 patients with cutaneous Darier's disease. Oral lesions comprising whitish papules of varying severity were present in 12 patients, with the palate being the most common site affected, followed by gingiva, buccal mucosa and tongue. Generally, the severity of the oral lesions paralleled that of the skin condition. Seven patients (30%), six of whom also had oral mucosal involvement, reported intermittent parotid swelling. Parotid sialograms of two patients revealed strictures in the main ducts, suggesting an obstructive aetiology.
R I Macleod; C S Munro
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  British dental journal     Volume:  171     ISSN:  0007-0610     ISO Abbreviation:  Br Dent J     Publication Date:  1991 Sep 
Date Detail:
Created Date:  1991-12-05     Completed Date:  1991-12-05     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  7513219     Medline TA:  Br Dent J     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  133-6     Citation Subset:  D; IM    
Department of Oral Pathology, Newcastle Dental School.
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MeSH Terms
Darier Disease / pathology*
Middle Aged
Mouth Diseases / pathology*
Mouth Mucosa / pathology
Parotid Diseases / radiography*
Parotid Gland / pathology,  radiography

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