Document Detail


The incidence of dipyrone-induced agranulocytosis in Greece during 1975.
MedLine Citation:
PMID:  520659     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A retrospective epidemiological study was conducted in Greece during 1975 to assess the incidence of agranulocytosis following treatment with dipyrone. Twenty-four cases of agranulocytosis were reported, of which fifteen were possibly associated with medication. If all fifteen cases are attributed to dipyrone, the incidence of agranulocytosis following treatment with this drug lies between one case in every 133,000 and one case in every 466,000 treatments.
Authors:
D D Varonos; S Santamouris; S Karambali
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of international medical research     Volume:  7     ISSN:  0300-0605     ISO Abbreviation:  J. Int. Med. Res.     Publication Date:  1979  
Date Detail:
Created Date:  1980-03-17     Completed Date:  1980-03-17     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0346411     Medline TA:  J Int Med Res     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  564-8     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Agranulocytosis / chemically induced*,  epidemiology
Aminopyrine / analogs & derivatives*
Child
Dipyrone / adverse effects*
Female
Greece
Humans
Male
Middle Aged
Retrospective Studies
Chemical
Reg. No./Substance:
58-15-1/Aminopyrine; 68-89-3/Dipyrone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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