Document Detail

The incidence of cutting fluid dermatitis among metalworkers in a metal fabrication factory: a prospective study.
MedLine Citation:
PMID:  7750250     Owner:  NLM     Status:  MEDLINE    
We compared the incidence of occupational dermatitis and transepidermal water vapour loss (TEWL) changes from cutting fluids (neat mineral oils) in 24 new machinists with 27 armed forces paramedics (controls) over a 6-month period. The cumulative incidence of occupational dermatitis in positive controls increased from 38% at week 3 to 77% at week 6. It then decreased to 50% at week 9 and thereafter remained constant at about 50% throughout the remaining study period. 2 workers sought medical treatment for their dermatitis. Only 1 worker had a job transfer because of his dermatitis. None of the paramedics developed dermatitis during the study period. The mean basal TEWL values on the hands of machinists and controls were 17.6 and 14.5 g/m2/h (n.s.) respectively. The mean TEWL values of machinists increased to 22 g/m2/h by week 3 and then remained fairly constant throughout the remaining study period. The mean TEWL of negative controls remained fairly constant (at about 14 g/m2/h) from the beginning to the end of the study period. The mean TEWL value of machinists was significantly higher than that of negative controls throughout the study period. There was no significant difference in the prevalence of cutting fluid dermatitis between machinists with high basal TEWL values (> or = 17 g/m2/h) and those with low basal TEWL values (< 17 g/m2/h).
C L Goh; S L Gan
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Contact dermatitis     Volume:  31     ISSN:  0105-1873     ISO Abbreviation:  Contact Derm.     Publication Date:  1994 Aug 
Date Detail:
Created Date:  1995-06-22     Completed Date:  1995-06-22     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7604950     Medline TA:  Contact Dermatitis     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  111-5     Citation Subset:  IM    
National Skin Centre, Singapore.
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MeSH Terms
Case-Control Studies
Dermatitis, Irritant / etiology*,  physiopathology
Dermatitis, Occupational / etiology*,  physiopathology
Hand Dermatoses / chemically induced,  physiopathology
Mineral Oil / adverse effects*
Prospective Studies
Water Loss, Insensible
Reg. No./Substance:
8020-83-5/Mineral Oil

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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