Document Detail

The incidence and cause of coagulopathies in an intensive care population.
MedLine Citation:
PMID:  8639449     Owner:  NLM     Status:  MEDLINE    
We studied 235 patients admitted to an adult intensive care unit in order to determine the incidence and cause of coagulation disturbances. Clinical coagulopathy, defined as bleeding unexplained by local or surgical factors, was identified in 13.6% of patients. Laboratory evidence of coagulopathy was more common: a prothrombin time (PT) ratio > or = 1.5 was found in 66% of patients and a platelet count <100 x 10(9)/l in 38% of patients. Both factors were predictive of excessive bleeding and poor outcome. In a retrospective analysis of plasmas from 45 of the above patients who had PT ratios > or = 1.5 the most common cause was vitamin K deficiency (20%).
R Chakraverty; S Davidson; K Peggs; P Stross; C Garrard; T J Littlewood
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  British journal of haematology     Volume:  93     ISSN:  0007-1048     ISO Abbreviation:  Br. J. Haematol.     Publication Date:  1996 May 
Date Detail:
Created Date:  1996-07-15     Completed Date:  1996-07-15     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0372544     Medline TA:  Br J Haematol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  460-3     Citation Subset:  IM    
Department of Haematology, Oxford-Radcliffe NHS Trust, Oxford, UK.
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MeSH Terms
Blood Coagulation Disorders / epidemiology,  etiology*,  therapy
Intensive Care Units
Length of Stay
Middle Aged
Prospective Studies
Retrospective Studies
Thrombin Time
Thrombocytopenia / complications
Vitamin K Deficiency / complications

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