| An in vivo model for studying the local haemodynamics of end-to-side anastomoses. | |
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MedLine Citation:
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PMID: 7627648 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVES: To develop an in-vivo model to study the anastomotic flow patterns. DESIGN: Prospective, open, animal study. METHODS: Polyurethane grafts with an internal diameter equal to the abdominal aorta (8 mm) of 90 kg pigs were implanted as bypass grafts from the supra-renal to the infra-renal level. A novel technique for constructing anastomoses with different anastomosis angles and only slight dilatation was used. The proximal outflow segment was occluded and the flow rate through the graft controlled by clamping the iliac arteries. Visualisation of the flow-fields at the distal end-to-side anastomosis was achieved by a comprehensive colour Doppler mapping protocol. RESULTS: The angulation of the anastomoses was controllable and reproducible. Gross haemodynamic parameters were stable within physiological ranges and were typical for peripheral bypass grafts. The flow fields at the distal end-to-side anastomosis were visualised and found to be in accordance with those reported by in vitro studies. Using different angles of Doppler insonation the same flow field characteristics were found. CONCLUSIONS: The model is an appropriate tool for studies of the effects of anastomotic geometry on local flow fields in vivo. |
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Authors:
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N H Staalsen; E M Pedersen; M Ulrich; J Winther; T V How; J M Hasenkam |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery Volume: 9 ISSN: 1078-5884 ISO Abbreviation: Eur J Vasc Endovasc Surg Publication Date: 1995 Feb |
Date Detail:
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Created Date: 1995-09-05 Completed Date: 1995-09-05 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9512728 Medline TA: Eur J Vasc Endovasc Surg Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 152-61 Citation Subset: IM |
Affiliation:
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Department of Thoracic and Cardiovascular Surgery, Skejby Hospital, Denmark. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Anastomosis, Surgical*
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methods Animals Aorta, Abdominal / physiology*, surgery*, ultrasonography Blood Flow Velocity Blood Vessel Prosthesis* Blood Viscosity Constriction Disease Models, Animal Heart Rate Hemodynamics Iliac Artery Pilot Projects Polytetrafluoroethylene Prospective Studies Prosthesis Design Regional Blood Flow Renal Artery / surgery Surface Properties Swine Ultrasonography, Doppler, Color |
| Chemical | |
Reg. No./Substance:
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9002-84-0/Polytetrafluoroethylene |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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